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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205327/
Sep 01, 2011 · Tumor-targeted drug delivery is one of the major areas in cancer research. Aptamers exhibit many desirable properties for tumor-targeted drug delivery, such as ease of selection and synthesis, high binding affinity and specificity, low immunogenicity, and …Author: Yin Zhang, Hao Hong, Weibo Cai
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033951/
This proof-of-principle study demonstrated that an anti-TN-C aptamer could be used to target tumors (glioma, breast, and colon) that express high level of TN-C and that aptamers, in general, may have pharmacologic properties that make them excellent agents for tumor-specific drug delivery.Author: Partha Ray, Rebekah R. White
https://www.researchgate.net/publication/51568610_Tumor-Targeted_Drug_Delivery_with_Aptamers
Tumor-targeted drug delivery is one of the major areas in cancer research. Aptamers exhibit many desirable properties for tumor-targeted drug delivery, such as ease of selection and synthesis, high...
http://www.eurekaselect.com/openurl/content.php?genre=article&issn=0929-8673&volume=18&issue=27&spage=4185
Tumor-targeted drug delivery is one of the major areas in cancer research. Aptamers exhibit many desirable properties for tumor-targeted drug delivery, such as ease of selection and synthesis, high binding affinity and specificity, low immunogenicity, and versatile synthetic accessibility.Author: Yin Zhang, Hao Hong, Weibo Cai
https://pubs.acs.org/doi/10.1021/nn901374b
Aptamer-Based Tumor-Targeted Drug Delivery for Photodynamic Therapy ACS Nano A specialized G-rich DNA structure, G-quadruplex, has been studied for its special physical characteristics and biological effects. Herein we report a novel strategy of using G-quadruplex as a drug carrier to target cancer cells for photodynamic therapy (PDT).Author: Yen-An Shieh, Shu-Jyuan Yang, Ming-Feng Wei, Ming-Jium Shieh
https://www.ncbi.nlm.nih.gov/pubmed/31099007
Cancer-related aptamers can be used for tumor-targeted drug delivery, such as to deliver diagnostic and therapeutic radionuclides to target cancers. We describe the process for preparing a 64Cu-labeled modified A10 aptamer to target prostate cancer by conjugating and radiolabeling.Author: Lei Kang, Zachary T. Rosenkrans, Weibo Cai
https://onlinelibrary.wiley.com/doi/full/10.1002/adtp.201800091%4010.1002/%28ISSN%292366-3987.editors-choice
The overexpression of receptors on cancerous cells can be exploited for tumor‐targeted drug delivery. The authors discuss the most promising receptor targets and drug delivery vehicles to enhance the...
http://www.eurekaselect.com/111247/article?tracking-code=4
Aptamer researches applied to the treatment of human cancers have increased since their discovery in 1990. This is due to different factors including: 1) t...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043981/
Oct 30, 2010 · Applications of antitumor drugs (such as docetaxel, dextran, cisplatin, daunorubicin, and doxorubicin) are limited due to their side effects/toxicity. The first report of targeted drug delivery with nanoparticle-aptamer bioconjugates was described by Farokhzad et al. in 2004 (Fig. 1D) (Farokhzad et al., 2004).Author: Jiehua Zhou, John J. Rossi
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992821/
Mar 23, 2009 · Conjugation of the drug doxorubicin (Dox) to aptamer sgc8c for targeted delivery to cancer cells. sgc 8 c (M) = A 260 − (ε 260 × A 495 / ε 495) 397600 (A is the observed absorbance at noted wavelength), which includes a correction for the absorbance of Dox at the same wavelength (ε 260 = 24000 cm −1 M −1).Author: Yu Fen Huang, Dihua Shangguan, Haipeng Liu, Joseph A. Phillips, Xiaoling Zhang, Xiaoling Zhang, Yan ...
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