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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890026/
Tumor-targeted drug delivery and MRI contrast enhancement by chlorotoxin-conjugated iron oxide nanoparticles Conroy Sun , 1 Chen Fang , 1 Zachary Stephen , 2 Omid Veiseh , 1 Stacey Hansen , 3 Donghoon Lee , 4 Richard G. Ellenbogen , 5 Jim Olson , 3 and Miqin Zhang *, 1, 4, 5Author: Conroy Sun, Chen Fang, Zachary Stephen, Omid Veiseh, Stacey Hansen, Donghoon Lee, Richard G. Ellenbo...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047275/
Feb 26, 2020 · 2. Size Impact on Delivery Efficacy. As one of the most important characteristics of nanoparticles, size greatly influences the efficiency of tumor targeted drug delivery in many ways, including circulation, biodistribution, tumor accumulation and penetration, as well as cellular uptake and subcellular distribution.
https://www.sciencedirect.com/science/article/pii/S0168365918305807
Although graphene oxide has been widely used in tumor-targeted drug delivery system as a good photothermal material and can be loaded with the anti-tumor drug such as cisplatin, it is difficult to carry a highly soluble drug, thus limiting its development[, , , , ].Author: Zhe Wang, Yaou Duan, Yanwen Duan
https://www.slideshare.net/tasnimfarihanoshin/targeted-drug-delivery-to-tumor
Mar 20, 2015 · Targeted drug delivery to tumor 1. Tasnim fariha noshin Nazmul huda Farzana naznin Ariful islam Noakhali Science & Technology University, Pharmacy Dpt. 2. Tumors are a classic sign of inflammation. It is a fluid-filled lesion that may or may not be formed by an abnormal growth of neoplastic cells that appears enlarged in size. 3.
https://pubs.acs.org/doi/abs/10.1021/acsabm.9b01244
Developing of multifunctional nanoplateforms for simultaneous accurate cancer detection and target therapy is essential in cancer treatment. Herein, we present a facile synthesis of DOX/MNPs-FA nanocomposites for high-performance MRI and tumor-targeted drug delivery. In such core–shell structured DOX/MNPs-FA nanocomposite, the high magnetism of iron oxide core can be tuned and …Author: Weijun Fang, Wenjuan Zhu, Hu Chen, Hanyuan Zhang, Shi Hong, Wenmei Wei, Tingting Zhao
https://www.researchgate.net/publication/261746437_Magnetic_Resonance_Imaging-Visible_and_pH-Sensitive_Polymeric_Micelles_for_Tumor_Targeted_Drug_Delivery
Magnetic Resonance Imaging-Visible and pH-Sensitive Polymeric Micelles for Tumor Targeted Drug Delivery. ... micelles as a MRI-visible drug delivery system with activ e.
http://www.authorstream.com/Presentation/legendpoluprasad-2207763-tumor-targeting-ppt/
Jul 13, 2014 · Targeted drug delivery Targeted drug delivery system is achieved with the advantage of morphology and physiological differences between the normal cells and tumor cells. An ideal anticancer drug delivery system should fulfill the following requirements Effectively kill tumor cells Be non-toxic for healthy organs, tissues, and cells Not induce ...
https://www.sciencedirect.com/science/article/pii/S0142961212001858
The kinetics of drug uptake was consistent with MR imaging: a good correlation was observed between the LC/MS measured drug uptake and f Vol H determined by MRI (Fig. 4d, R 2 = 0.97), suggesting that drug delivery could be quantified non-invasively. A similar MR study was conducted in s.c PC3, MDA-MB-231, and B16F10 models which were treated ...Author: Mark J. Ernsting, Warren D. Foltz, Elijus Undzys, Tatsuaki Tagami, Shyh-Dar Li
https://www.researchgate.net/publication/261405000_Brain_Tumor-targeted_Drug_Delivery_Strategies
Brain tumor-targeted drug delivery systems, which increase drug accumulation in the tumor region and reduce toxicity in normal brain and peripheral tissue, are a promising new approach to brain ...
http://www.authorstream.com/Presentation/siri1515-1478182-tumor-cancer-neoplastic-targeted-drug-delivery/
There are two broad classes of tumor targeted drug delivery systems. Macromolecular conjugates Particulate systems 10 EPR effect can only be applied to macromolecular Drug delivery systems, as small molecule drugs leak through the capillary pores of normal vessels too! Lammers T et al. Br J Cancer. 2008;99:392 - 397. Contd…
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