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https://www.nature.com/articles/nrd1775
Jul 01, 2005 · Design and development of polymers for gene delivery. ... is necessary to understand the limitations of cationic polymers and is important for the rational design of new polymers.Author: Daniel W. Pack, Allan S. Hoffman, Suzie Pun, Patrick S. Stayton
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079258/
Mar 01, 2011 · Various bioreducible polymers have been developed for gene delivery systems because the above unique features make bioreducible polymers as ideal gene delivery carriers. This review will focus the initiation and recent advances in the development and application of bioreducible polymers for gene delivery systems.Author: Tae Il Kim, Sung Wan Kim, Sung Wan Kim
http://www.nature.com/articles/doi:10.1038/nrd1775
Jul 01, 2005 · The lack of safe and efficient gene-delivery methods is a limiting obstacle to human gene therapy. Synthetic gene-delivery agents, although safer than recombinant viruses, generally do …
https://www.sciencedirect.com/science/article/pii/S016777991830060X
Current Development of Polymeric Carriers. Gene delivery technologies may bring hope of combating diseases that have been pharmaceutically intractable. ... These technologies can help to extend the flexibility and versatility in design of polymers for gene delivery. Along with the increasing understanding of the mechanisms of cellular ...Author: Wing-Fu Lai, Wing-Fu Lai, Wing-Tak Wong
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417261/
Mar 12, 2019 · The non-viral gene delivery systems have also treated for the physicochemical approaches such as physical method and chemical method. Several kinds of gene delivery systems have discussed on the gene delivery systems of cationic biomedical polymers such as polysaccharides, polyethylenimine (PEI), and poly(L-lysine)(PLL) derivatives.Author: YK Sung, SW Kim
https://nebraska.pure.elsevier.com/en/publications/design-and-development-strategies-of-polymer-materials-for-drug-a
Jun 10, 2008 · TY - JOUR. T1 - Design and development strategies of polymer materials for drug and gene delivery applications. AU - Oupicky, David. PY - 2008/6/10Author: David Oupicky
https://www.mdpi.com/journal/polymers/special_issues/polymers_in_gene_delivery
The major obstacle facing efficient gene therapy is the development of reliable delivery vehicles, which are both nontoxic and biocompatible and possess efficient cell-specific gene delivery. Previously, hybrid delivery vehicles comprising anionic liposomes and cationic polymers have been used successfully for …
https://www.researchgate.net/publication/7694030_Pack_DW_Hoffman_AS_Pun_S_and_Stayton_PS_Design_and_development_of_polymers_for_gene_delivery_Nat_Rev_Drug_Discov_4_581-593
Request PDF Pack, DW, Hoffman, AS, Pun, S and Stayton, PS. Design and development of polymers for gene delivery. Nat Rev Drug Discov 4: 581-593 The lack of safe and efficient gene-delivery ...
https://www.mdpi.com/2073-4360/11/4/745
In 1987, Felgner et al. used the cationic lipid based non-viral gene delivery system for the very first time. This breakthrough opened the opportunity for other non-viral vectors, such as polymers. Cationic polymers have emerged as promising candidates for non-viral gene delivery systems because of their facile synthesis and flexible properties.Author: Raj Rai, Saniya Alwani, Ildiko Badea
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