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https://www.annualreviews.org/doi/abs/10.1146/annurev.bioeng.10.061807.160544
Thus, for specific disease treatment with costly and/or aggressive medicine, it is necessary to provide targeted drug–aerosol delivery to predetermined sites in the human respiratory system. Experimental measurements and computer models of particle transport and deposition in …Author: C. Kleinstreuer, Z. Zhang, J.F. Donohue
https://www.researchgate.net/publication/5439190_Targeted_Drug-Aerosol_Delivery_in_the_Human_Respiratory_System
Request PDF Targeted Drug-Aerosol Delivery in the Human Respiratory System Inhalation of drug aerosols is a modern pathway to combat lung diseases. It is also becoming the preferred route for ...
https://www.annualreviews.org/doi/10.1146/annurev.bioeng.10.061807.160544
Thus, for specific disease treatment with costly and/or aggressive medicine, it is necessary to provide targeted drug–aerosol delivery to predetermined sites in the human respiratory system. Experimental measurements and computer models of particle transport and deposition in …Author: C. Kleinstreuer, Z. Zhang, J.F. Donohue
https://royalsocietypublishing.org/doi/10.1098/rsos.170873
In the present study, in addition to a passive distribution of inhaled aerosols, we would like to analyse the potential of a controlled drug-aerosol delivery in the anatomically realistic human respiratory system, based on the magnetic drug targeting (MDT) concept.Author: Saša Kenjereš, Jimmy Leroy Tjin
https://www.semanticscholar.org/paper/Targeted-drug-aerosol-delivery-in-the-human-system.-Kleinstreuer-Zhang/0ab075c476e48ea9d5911276bac002a0c8c2f7e3
2008; DOI: 10.1146/annurev.bioeng.10.061807.160544 Targeted drug-aerosol delivery in the human respiratory system. @article{Kleinstreuer2008TargetedDD, title={Targeted drug-aerosol delivery in the human respiratory system.}, author={Clement Kleinstreuer and Zhe Zhang and James F Donohue}, journal={Annual review of biomedical engineering}, year={2008}, volume={10}, pages={ 195-220 } }
https://www.researchgate.net/profile/Clement_Kleinstreuer/publication/234146154_Zhang_Z_Airflow_and_Particle_Transport_in_the_Human_Respiratory_System_Annu_Rev_Fluid_Mech_42_301-334/links/56cf2d7e08ae4d8d649fa1e0/Zhang-Z-Airflow-and-Particle-Transport-in-the-Human-Respiratory-System-Annu-Rev-Fluid-Mech-42-301-334.pdf
inhalation has been reviewed by Phalen (2009), whereas targeted drug-aerosol delivery in the human respiratory system has been discussed by Kleinstreuer et al. (2008). 2.
https://www.deepdyve.com/lp/annual-reviews/targeted-drug-aerosol-delivery-in-the-human-respiratory-system-RXWVWbEycB
Aug 15, 2008 · Targeted Drug-Aerosol Delivery in the Human Respiratory System Targeted Drug-Aerosol Delivery in the Human Respiratory System Kleinstreuer, C.; Zhang, Z.; Donohue, J.F. 2008-08-15 00:00:00 Inhalation of drug aerosols is a modern pathway to combat lung diseases. It is also becoming the preferred route for insulin delivery, pain management, cancer therapy, and nanotherapeutics.
https://www.sciencedirect.com/science/article/pii/S0017931008002688
A new methodology for targeting drug-aerosols in the human respiratory system. ... Targeted drug-aerosol delivery to desired lung areas required for the treatment of a specific disease is becoming more and more a treatment option, because it is fast, convenient, and with reduced topical side effects. ...Author: Clement Kleinstreuer, Zhe Zhang, Zheng Li, William L. Roberts, Carlye Rojas
https://www.sciencedirect.com/science/article/abs/pii/S0017931008002688
A new methodology for targeting drug-aerosols in the human respiratory system. ... the popular pressurized metered dose inhalers and dry powder inhalers have rather low deposition efficiencies and their drug-aerosol deliveries are non-directional. This is acceptable when the medicine is inexpensive and does not cause systemic side effects, as ...Author: Clement Kleinstreuer, Zhe Zhang, Zheng Li, William L. Roberts, Carlye Rojas
http://rc.rcjournal.com/content/59/10/1608
Oct 01, 2014 · The primary mechanisms of lung deposition of inhaled respirable drug aerosol particles in the human lung consist of the 5 electromechanical processes: impaction, diffusion, interception, gravitational settling, and electrostatic effects, as depicted in Figure 1. 1,2 There are a number of mathematical models and computational tools developed to ...Author: Mohammed Ali
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