We have collected information about Transdermal Delivery Heparin Skin Electroporation for you. Follow the links to find out details on Transdermal Delivery Heparin Skin Electroporation.
https://www.nature.com/articles/nbt1195-1205
To increase transport of a highly-charged macromolecule (heparin), high-voltage pulses believed to cause electroporation were applied to skin. Using this approach, transdermal heparin transport ...Author: Prausnitz Mr, Prausnitz Mr, Edelman Er, Edelman Er, Gimm Ja, Langer R, Weaver Jc
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810085/
Mar 17, 2016 · Electroporation-mediated transdermal delivery of selected compounds across different skin models is shown in Table 1. Blagus et al. used a new in vivo real-time monitoring system based on fluorescently labeled molecules for the quantification of transdermal and topical drug delivery [ 18 ].Author: Kevin B. Ita
https://reference.medscape.com/medline/abstract/9636293
Transdermal delivery would be an attractive solution, except macromolecules have not previously been delivered clinically across human skin at therapeutic rates. To increase transport of a highly-charged macromolecule (heparin), high-voltage pulses believed to cause electroporation were applied to skin.
https://www.researchgate.net/publication/12600465_Transdermal_Delivery_of_Macromolecules_Using_Skin_Electroporation
(1) To evaluate the feasibility of transdermal delivery of macromolecules by skin electroporation. (2) To assess the influence of the molecular weight of the permeant on transport and examine ...
https://www.sciencedirect.com/science/article/pii/S0378517315303690
1.2. Electroporation-assisted delivery of heparin. Transdermal electroporation, which is also called electropermeabilization, takes place when the skin is exposed to high electric field pulses (García-Sánchez et al., 2015). Molecules are able to cross the stratum corneum when the optimal electroporation parameters are chosen.Author: Kevin Ita
https://www.sciencedirect.com/science/article/pii/S0169409X03002436
About 10 years ago, the use of electroporation for transdermal delivery was suggested .Although the technique is normally used on the unilamellar phospholipid bilayers of cell membranes, it has been demonstrated that electroporation of skin is feasible, even though the stratum corneum contains multilamellar, intracellular lipid bilayers with few phospholipids , , , .Author: Anne-Rose Denet, Rita Vanbever, Véronique Préat
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700785/
Transdermal delivery represents an attractive alternative to oral delivery of drugs and is poised to provide an alternative to hypodermic injection too 1 – 4.For thousands of years, people have placed substances on the skin for therapeutic effects and, in the modern era, a variety of topical formulations have been developed to treat local indications.Author: Mark R Prausnitz, Robert Langer
Searching for Transdermal Delivery Heparin Skin Electroporation?
You can just click the links above. The data is collected for you.
