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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293995/
Lilley CE, et al. Multiple immediate-early gene-deficient herpes simplex virus vectors allowing efficient gene delivery to neurons in culture and widespread gene delivery to the central nervous system in vivo. J Virol. 2001; 75:4343–56. [PMC free article] Liu J, et al. 3D …Author: Thomas B. Lentz, Steven James Gray, R. Jude Samulski
https://www.nature.com/articles/nrn1104
May 01, 2003 · The use of viral vectors to deliver genes to the nervous system shows great promise for both basic research and therapeutic applications. However, the brain presents a …Author: Beverly L. Davidson, Xandra O. Breakefield
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507026/
Jul 06, 2012 · Viral and nonviral delivery systems for gene delivery. Nouri Nayerossadat, 1, 2 Talebi Maedeh, 1 and Palizban Abas Ali 3 ... it has the greatest potential for gene delivery to nervous system, ... are major limitations in utilizing the viral vectors in gene therapy.
https://www.sciencedirect.com/science/article/pii/S0969996111003275
Introduction: viruses as vectors for therapeutic gene delivery. The idea to treat human disease by delivering a therapeutic gene was first conceived as early as the 1970s (Friedmann and Roblin, 1972).The potential of viruses as vectors for gene delivery was recognized even then.Author: Thomas B. Lentz, Steven James Gray, R. Jude Samulski
https://www.sciencedirect.com/science/article/abs/pii/S0969996111003275
In this review, we outline desired features of the ideal vector for gene delivery to the CNS and discuss how well available viral vectors compare to this model. Adeno-associated virus, retrovirus, adenovirus and herpesvirus vectors are covered.Author: Thomas B. Lentz, Steven James Gray, R. Jude Samulski
https://houptlab.org/courses/cmn/transgenic/Davidson2003.pdf
VIRAL VECTORS FOR GENE DELIVERY TO THE NERVOUS SYSTEM Beverly L. Davidson* and Xandra O. Breakefield ‡ Our ability to manipulate the genetic constitution of the nervous system has come of age with various technologies, including virus vectors that can efficiently deliver genes to neurons and other neural cells in vitro and in vivo. These ...
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