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https://www.ncbi.nlm.nih.gov/pubmed/15526161
Polymeric micelles (micelles formed by amphiphilic block copolymers) demonstrate a series of attractive properties as drug carriers, such as high stability both in vitro and in vivo and good biocompatibility, and can be successfully used for the solubilization of various poorly soluble pharmaceuticals. These micelles can also be used as targeted drug delivery systems.Author: V. P. Torchilin
https://link.springer.com/article/10.1007%2Fs00018-004-4153-5
Polymeric micelles (micelles formed by amphiphilic block copolymers) demonstrate a series of attractive properties as drug carriers, such as high stability both in vitro and in vivo and good biocompatibility, and can be successfully used for the solubilization of various poorly soluble pharmaceuticals. These micelles can also be used as targeted drug delivery systems.Author: V. P. Torchilin
https://onlinelibrary.wiley.com/doi/10.1002/9781118444726.ch14
Polymeric micelles have found wide application as pharmaceutical nanocarriers for the delivery of poorly soluble drugs. The poorly water‐soluble drugs can easily get trapped in the hydrophobic core of the micelle, while the hydrophilic shell is responsible for micelle stabilization and interaction with various proteins when in the biological system.Author: Swati Biswas, Onkar S. Vaze, Sara Movassaghian, Vladimir P. Torchilin
https://www.researchgate.net/publication/8194748_Targeted_polymeric_micelles_for_delivery_of_poorly_soluble_drugs
This new family of pharmaceutical carriers can be used for the solubilization and targeted delivery of poorly soluble drugs to various pathological sites in the body.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113619/
Apr 04, 2014 · Polymeric micelles are extensively studied carriers for the delivery of poorly water-soluble drugs. By enhancing the aqueous solubility and prolonging the blood half-life of chemotherapeutic agents, the anticancer agents can passively accumulate in the tumor site through the leaky vasculature via the enhanced permeability and retention (EPR) effect ( 1 , 2 ).Author: Yifei Zhang, Yixian Huang, Song Li
https://link.springer.com/article/10.1208%2Fs12249-014-0113-z
Apr 04, 2014 · Polymeric micelles represent an effective delivery system for poorly water-soluble anticancer drugs. With small size (10–100 nm) and hydrophilic shell of PEG, polymeric micelles exhibit prolonged circulation time in the blood and enhanced tumor accumulation.Author: Yifei Zhang, Yixian Huang, Song Li
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