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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646442/
Thermoresponsive hydrogels appear to be a promising, minimally invasive platform for extended drug delivery to the posterior segment. INTRODUCTION Vascular endothelial growth factor (VEGF) has been identified as a key regulator of angiogenesis.Author: Jennifer J. Kang Derwent, William F. Mieler
https://pubs.acs.org/doi/10.1021/acs.biomac.0c00077
According to these findings, the dual supramolecular hydrogel developed in this work with remarkable thermoresponsive properties might have potential for sustained anticancer drug delivery with enhanced therapeutic effect in multidrug-resistant cancer cells.Author: Xia Song, Zhongxing Zhang, Jingling Zhu, Yuting Wen, Feng Zhao, Lijie Lei, Nhan Phan-Thien, Boo Cheo...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415431/
Apr 27, 2018 · PF127 based thermoresponsive hydrogels are the best alternative for developing effective drug delivery systems as they display sol-gel transition near body temperature and the cell toxicity, biodegradability of PF127 based hydrogels has already been proven.Author: Sudipta Chatterjee, Patrick Chi-leung Hui, Chi-wai Kan
https://www.researchgate.net/publication/51118830_Thermosensitive_hydrogels_for_drug_delivery
Thermosensitive hydrogel-based drug delivery systems have increasingly attracted the attention of the drug delivery community, as the drugs can be readily encapsulated and released by the hydrogels.
https://www.sciencedirect.com/science/article/pii/S0939641107002470
Interestingly, when the hydrogel was tested for drug delivery, it was shown that a low molecular weight drug (methylene blue) was released slower at 25 °C than at 37 °C, whereas the opposite was observed for a high molecular weight substance (bovine serum albumin – BSA) . The authors concluded that the drug release profile depends on a number of factors, as the temperature, the swelling and …Author: Leda Klouda, Antonios G. Mikos
https://www.researchgate.net/publication/232646895_Thermosensitive_Polymeric_Hydrogels_As_Drug_Delivery_Systems
Thermosensitive hydrogels are very important biomaterials used in drug delivery systems (DDSs), which gained increasing attention of researchers. Thermosensitive hydrogels have great potential in various applications, such as drug delivery, cell encapsulation, tissue engineering, and etc.
https://pubs.acs.org/doi/abs/10.1021/acs.biomac.9b01009
The hydrogel gave a sustained and controlled linear release of G(IIKK)3I-NH2 over time. Using the peptide nanofibrils as three-dimensional scaffolds, such thermoresponsive hydrogels mimic the extracellular matrix and could potentially be used as injectable hydrogels for minimally invasive drug delivery or tissue engineering.Author: Meiwen Cao, Yu Wang, Xuzhi Hu, Haoning Gong, Ruiheng Li, Henry Cox, Jing Zhang, Thomas A. Waigh, Hai...
https://www.sciencedirect.com/science/article/pii/S1818087614000634
Thermoresponsive polymers are used for biomedical applications including drug delivery, tissue engineering and gene delivery , , , , . Temperature-responsive polymers exhibit a volume phase transition at a certain temperature, which causes a sudden change in the solvation state.Author: Arijit Gandhi, Abhijit Paul, Suma Oommen Sen, Kalyan Kumar Sen
https://chitolytic.com/responsive-hydrogels/
The system has potential for thermoresponsive and enzymatically degradable drug delivery. Supramolecular and other in situ-forming hydrogels are particularly interesting due to their rheological versatility; in sol form, they may possess a viscosity suitable for injection-based treatments, fol-lowed by gel-phase transition upon exposure to physiological conditions [40].
https://www.sciencedaily.com/releases/2019/09/190918093103.htm
Sep 18, 2019 · Bio-engineering researchers have created a biocompatible, protein-based hydrogel that could serve as a drug delivery system durable enough to survive in …
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