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https://www.thermofisher.com/us/en/home/references/gibco-cell-culture-basics/transfection-basics/gene-delivery-technologies.html
Technology Advantages Disadvantages; Viral delivery: Highest efficiency amongst gene delivery methods (80–90% transduction efficiency in primary cells) Works well with difficult to transfect cell types; Can be used for in vivo delivery of nucleic acids
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915088/
Jan 15, 2014 · Lipids. Among the non-viral vectors, liposomes based on cationic lipids are by far the most common gene delivery systems and have been the subject of considerable interests as non-viral delivery vectors 49-50.Liposomes are synthetic lipid spheres composed by fatty acid on polymers with one or more bilayered membrane structure surrounding an aqueous core that can be used to encapsulate …Author: Lian Jin, Xin Zeng, Ming Liu, Yan Deng, Nongyue He
https://researchcores.partners.org/mvvc/about
The Gene Delivery Technology Core was established at Massachusetts General Hospital in 2017. Co-directed by Rachael Neve and Frederick Boyce, its overall goals are to provide the most advanced viral vector technologies, and to drive the development of new applications that …
https://engene.com/science/
Jul 10, 2017 · enGene has pioneered the oral delivery of DNA to gut mucosal cells using its Gene Pill™ platform. The technology at the core of Gene Pill™ is based on an internally developed DNA carrier made of a synthetic polymer named Dually Derivitized Oligochitosan (DDX®) that is optimized for packaging and transporting DNA into epithelial cells situated behind a mucous barrier.
https://blog.dana-farber.org/insight/2018/04/gene-therapy-used-treat-cancer/
Apr 02, 2018 · Gene therapy alters the genetic instructions within an individual’s cells. A gene is a sequence of DNA — pictured above. A variety of efforts are underway to apply gene therapy to cancer treatment. Most are in early, exploratory stages, where they’re …
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