Targeted Prodrug Design To Optimize Drug Delivery

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Targeted prodrug design to optimize drug delivery

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751001/
    On the other hand, targeted prodrug design represents a new strategy for directed and efficient drug delivery. Particularly, targeting the prodrugs to a specific enzyme or a specific membrane transporter, or both, has potential as a selective drug delivery system in cancer chemotherapy or as an efficient oral drug delivery system.Author: Hyo Kyung Han, Gordon L. Amidon

Targeted prodrug design to optimize drug delivery.

    https://www.ncbi.nlm.nih.gov/pubmed/11741222
    On the other hand, targeted prodrug design represents a new strategy for directed and efficient drug delivery. Particularly, targeting the prodrugs to a specific enzyme or a specific membrane transporter, or both, has potential as a selective drug delivery system in cancer chemotherapy or as an efficient oral drug delivery system.Author: Hyo Kyung Han, Gordon L. Amidon

Targeted prodrug design to optimize drug delivery ...

    https://link.springer.com/article/10.1208%2Fps020106
    Mar 01, 2000 · On the other hand, targeted prodrug design represents a new strategy for directed and efficient drug delivery. Particularly, targeting the prodrugs to a specific enzyme or a specific membrane transporter, or both, has potential as a selective drug delivery system in cancer chemotherapy or as an efficient oral drug delivery system.Author: Hyo Kyung Han, Gordon L. Amidon

Targeted prodrug design to optimize drug delivery

    http://www.suli-pharma.com/uploads/lectures/Targeted_Prodrug_.pdf
    instability. On the other hand, targeted prodrug design represents a new strategy for directed and efficient drug delivery. Particularly, targeting the prodrugs to a specific enzyme or a specific membrane transporter, or both, has potential as a selective drug delivery system in cancer chemotherapy or as an efficient oral drug delivery system.

Targeted prodrug design to optimize drug delivery

    https://www.researchgate.net/publication/11615895_Targeted_prodrug_design_to_optimize_drug_delivery
    The targeted prodrug approach, in combination with gene delivery and controlled expression of enzymes and carrier proteins, is a promising strategy for precise and efficient drug delivery and ...

Modern Prodrug Design for Targeted Oral Drug Delivery

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271014/
    The classical approach for prodrug design uses the non-specific strategy of covalently modifying the drug of interest by attaching hydrophilic functionalities (e.g., phosphate, sulfate) to increase the solubility of the parent drug [8,9,10], or lipophilic moieties (e.g., ester) to …Author: Arik Dahan, Ellen M. Zimmermann, Shimon Ben-Shabat

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