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https://www.researchgate.net/publication/221794071_Synthetic_Nanocarriers_for_Intracellular_Protein_Delivery
Altogether, these results demonstrate the first intracellular delivery of recombinant PTEN using a synthetic delivery vehicle and highlight the potential of intracellular PTEN protein delivery as ...
http://www.eurekaselect.com/openurl/content.php?genre=article&issn=1389-2002&volume=13&issue=1&spage=82
Synthetic Nanocarriers for Intracellular Protein Delivery Author(s): Juanjuan Du , Jing Jin , Ming Yan , Yunfeng Lu . Department of Chemical and Biomolecular Engineering, University of California at Los Angeles, 5531 Boelter Hall, 420 Westwood Plaza, Los Angeles, California 90095.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829369/
Nanocarrier-based protein delivery approaches are attractive due to the tunable chemical properties of the carrier. Nanocarriers, such as, liposomes, polymer, supercharged proteins, nanoparticles, carbon nanotubes, etc. have been widely used for intracellular protein delivery.Author: Moumita Ray, Yi-Wei Lee, Federica Scaletti, Ruijin Yu, Ruijin Yu, Vincent M Rotello
https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201907484
Jul 31, 2019 · Various nanosized intracellular delivery carriers are known, including micelles, liposomes, synthetic vesicles, and polymersomes. 3 Micelles are highly dynamic assemblies of amphiphiles composed of a hydrophobic core and hydrophilic shell. 4 Their potential for intracellular delivery is limited since they can only encapsulate hydrophobic payloads, their critical micelle concentration is typically …Author: Sharafudheen Pottanam Chali, Bart Jan Ravoo
https://www.sciencedirect.com/science/article/pii/S0169409X20300193
Apr 01, 2020 · Optimizing synthetic nanocarriers is like searching for a needle in a haystack. How to find the most suitable carrier for intracellular delivery of a …
https://pubs.rsc.org/en/content/articlelanding/2011/cs/c0cs00227e
Intracellular protein delivery holds enormous promise for biological and medical applications, including cancer therapy, vaccination, regenerative medicine, treatment for loss-of-function genetic diseases and imaging. This tutorial review surveys recent developments in intracellular protein delivery using various nanocarriers.Author: Zhen Gu, Anuradha Biswas, Muxun Zhao, Yi Tang
https://pubs.rsc.org/en/content/articlelanding/2018/tb/c8tb00330k#!
The intracellular delivery of functional proteins in their native forms into cells is a theme of paramount importance in research owing to their diverse biological applications. Porous inorganic nanoparticles are emerging as efficient nanocarriers for the delivery of small molecules and drugs.
https://www.ncbi.nlm.nih.gov/pubmed/28338410
Intracellular delivery of proteins is potentially a game-changing approach for therapeutics. However, for most applications, the protein needs to access the cytosol to be effective. A wide variety of strategies have been developed for protein delivery, however access of delivered protein to the cytosol without acute cytotoxicity remains a ...Author: Moumita Ray, Yi-Wei Lee, Federica Scaletti, Ruijin Yu, Ruijin Yu, Vincent M Rotello
https://onlinelibrary.wiley.com/doi/abs/10.1002/adma.201902791?af=R
Rational Design of Nanocarriers for Intracellular Protein Delivery Xiaofei Qin Key Laboratory of Flexible Electronics (KLOFE) and Institute of Advanced Materials (IAM), Nanjing Tech University (NanjingTech), 30 South Puzhu Road, Nanjing, 211800 P. R. ChinaAuthor: Xiaofei Qin, Changmin Yu, Jing Wei, Lin Li, Chengwu Zhang, Qiong Wu, Jinhua Liu, Shao Q. Yao, Wei Hu...
https://pubs.acs.org/doi/10.1021/acsbiomaterials.8b01098
In contrast to several particulate systems like nanoparticles from metallic and inorganic/synthetic sources, the protein nanoparticles do not have limitations such as potential toxicity, large size, accumulation, or rapid clearance from the body.Author: Annish Jain, Sumit K. Singh, Shailendra K. Arya, Subhas C. Kundu, Sonia Kapoor, Sonia Kapoor
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