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https://www.ncbi.nlm.nih.gov/pubmed/20738181
Self-microemulsifying drug delivery system improves curcumin dissolution and bioavailability. Wu X(1), Xu J, Huang X, Wen C. Author information: (1)Institute of Clinical Pharmacology, Fujian Medical University, Fuzhou, PR China.Author: Xuemei Wu, Jianhua Xu, Xiuwang Huang, Caixia Wen
https://www.tandfonline.com/doi/abs/10.3109/03639045.2010.489560
Mar 27, 2014 · Background: Curcumin has a wide spectrum of biological and pharmacological activities, but it has not yet been approved as a therapeutic agent because of its low solubility and stability in aqueous solution, and the relatively low bioavailability in vivo. To overcome these limitations, self-microemulsifying drug delivery system (SMEDDS) of curcumin was developed.Author: Xuemei Wu, Jianhua Xu, Xiuwang Huang, Caixia Wen
https://www.researchgate.net/profile/Jianhua_Xu6/publication/45950463_Self-microemulsifying_drug_delivery_system_improves_curcumin_dissolution_and_bioavailability/links/02bfe510b0fc8a65c3000000/Self-microemulsifying-drug-delivery-system-improves-curcumin-dissolution-and-bioavailability.pdf
SMEDDS improves curcumin dissolution and bioavailability 17 (Shimadzu LC-20AB, Shimadzu Corporation, Kyoto, Japan)24. The effects of drug on the phase diagram. The following experiment was carried out to investigate the effects of curcumin on the self-emulsifying perfor- mance of SMEDDS.
https://reference.medscape.com/medline/abstract/20738181
BACKGROUND: Curcumin has a wide spectrum of biological and pharmacological activities, but it has not yet been approved as a therapeutic agent because of its low solubility and stability in aqueous...
https://www.researchgate.net/publication/45950463_Self-microemulsifying_drug_delivery_system_improves_curcumin_dissolution_and_bioavailability
the problems is the use of self-microemulsifying drug delivery system (SMEDD S) that consist of a mixture of drug, oil, surfactant, and cosurfactant, and the gentle
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674636/
Feb 06, 2015 · SEDDS is a stable mixture of drug, oil, surfactant, and co-surfactant; while self-microemulsifying drug delivery system (SMEDDS) is SEDDS which can form fine oil-in-water droplets with a diameter size of less than 50 nm under mild agitation of the gastrointestinal tract without the dissolution process .Author: Lan Wu, Yanli Qiao, Lina Wang, Jiahua Guo, Guocheng Wang, Wei He, Lifang Yin, Jinhua Zhao
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