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https://www.slideshare.net/chiranjibi68/rectal-drug-delivery-systems
Jun 22, 2016 · Such systems involves mucoadhesion , i.e. the attachment of the drug along with a suitable carrier to the mucous membrane. The rectal route though rarely the first choice of drug administration, serves as an alternative to oral and invasive administration. Rectal drug delivery is so pivotal when the oral medication is not possible, intra venous ...
https://www.tandfonline.com/doi/abs/10.1080/10837450.2018.1484766
Dec 28, 2017 · Novel rectal drug delivery systems including hollow-type suppositories, thermo-responsive and muco-adhesive liquid suppositories, and nanoparticulate systems incorporated into an appropriate vehicle have offered more control over delivery of drug molecules for local or systemic actions.Author: Trusha J. Purohit, Sara M. Hanning, Zimei Wu
https://www.researchgate.net/publication/313161191_RECTAL_DRUG_DELIVERY_SYSTEMS
Concepts, Formulation Approaches and Marketed Formulations Available and Evaluation Tests for RECTAL DRUG Delivery systems were explained with neat sketches. Discover the world's research.
http://www.authorstream.com/Presentation/AJ07-983761-rectal-drug-delivery-system/
Apr 27, 2011 · REASEARCH ARTICLE (cont.) : o smotically-powered rectal drug delivery system An osmotically-powered rectal drug delivery system, was used for the rectal infusion of the model drug antipyrine. The system, which is slightly larger than a normal suppository, has a nominal pumping rate of 43 μl h − 1 over at least 30 h.
https://www.slideshare.net/PrayasAcharya1/rectal-drug-delivery-systems-140201254
Apr 09, 2019 · Rectal Drug Delivery Systems 1. RECTAL MUCOSAL DRUG DELIVERY SYSTEM PRESENTED BY- PRAYAS ACHARYA PANKAJ GUPTA DEPARTMENT OF PHARMACEUTICAL SCIENCES AND TECHNOLOGY INSTITUTE OF CHEMICAL TECHNOLOGY, MUMBAI 1 2. S.N Contents 1 Introduction 2 Advantages & Disadvantages 3 Applications 4 Factors affecting rectal drug …
https://www.pharmatutor.org/articles/discussion-novel-rectal-drug-delivery-systems-recent-review
Rectal drug delivery systems used to deliver the drug by using mucoadhesive polymers is through the mucous membrane of the rectum. Rectal drug delivery is so essential when the oral medication is not possible, Intra venous(I.V) access is not possible and the patients have difficulty in swallowing, nausea and vomiting and for infants or children.
https://www.ncbi.nlm.nih.gov/pubmed/29888992
Advances in rectal drug delivery systems. Purohit TJ(1), Hanning SM(1), Wu Z(1). Author information: (1)a School of Pharmacy , The University of Auckland , Auckland , New Zealand. Drug delivery via the rectum is a useful alternative route of administration to the oral route for patients who cannot swallow.Author: Trusha J. Purohit, Sara M. Hanning, Zimei Wu
https://clinicalgate.com/rectal-and-vaginal-drug-delivery/
• Rectal and vaginal routes are used for local as well as systemic drug delivery and offer some unique advantages. • Both routes have a use in systemic drug delivery when the oral route is not available. • These routes are relatively less popular because of their anogenital nature and privacy aspects. • Local anti-infective drugs, hormones, lubricants, analgesics, anti-inflammatory ...
https://www.pharmaceutical-journal.com/news-and-analysis/features/exploring-the-unconventional-routes-rectal-and-vaginal-dosage-formulations/11105745.fullarticle?firstPass=false
However, drug delivery via the rectal cavity can be challenged by erratic drug absorption due to potential expulsion of the dosage form and low adhesion to the rectal membrane. In addition, drug bioavailability is affected by the site of drug absorption within the rectal cavity. The superior rectal veins go via the liver whereas the inferior ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215502/
Feb 07, 2010 · Introduction. Targeted drug delivery into the colon is highly desirable for local treatment of a variety of bowel diseases such as ulcerative colitis, Crohn’s disease, amebiosis, colonic cancer, local treatment of colonic pathologies, and systemic delivery of protein and peptide drugs.1, 2 The colon specific drug delivery system (CDDS) should be capable of protecting the drug en route to the ...Author: Anil K. Philip, Betty Philip
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