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https://www.slideshare.net/chiranjibi68/rectal-drug-delivery-systems
Jun 22, 2016 · CONCLUSION Rectal administration is truly explored as a potential drug delivery system particularly for drugs that are either too irritating for the gut or undergo extensive first pass metabolism. The rectal drug delivery system offer patients an option that is less invasive and the drug can be administered in unconscious and pediatric patients ...
http://www.authorstream.com/Presentation/AJ07-983761-rectal-drug-delivery-system/
Apr 27, 2011 · REASEARCH ARTICLE (cont.) : o smotically-powered rectal drug delivery system An osmotically-powered rectal drug delivery system, was used for the rectal infusion of the model drug antipyrine. The system, which is slightly larger than a normal suppository, has a nominal pumping rate of 43 μl h − 1 over at least 30 h.
https://www.tandfonline.com/doi/abs/10.1080/10837450.2018.1484766
Dec 28, 2017 · Drug delivery via the rectum is a useful alternative route of administration to the oral route for patients who cannot swallow. Traditional rectal dosage forms have been historically used for localized treatments including delivery of laxatives, treatment of hemorrhoids and for delivery of antipyretics.Author: Trusha J. Purohit, Sara M. Hanning, Zimei Wu
https://www.slideshare.net/GajananSanap/colon-targeted-drug-delivery-systems
Feb 27, 2016 · INTRODUCTION Targeted drug delivery systems: The major goal of any drug delivery system is to supply a therapeutic amount of drug to a target site in a body. Targeted drug delivery implies selective and effective localization of drug into the target at therapeutic concentrations with limited access to non target sites. A targeted drug delivery ...
https://www.researchgate.net/publication/313161191_RECTAL_DRUG_DELIVERY_SYSTEMS
An osmotically-powered rectal d rug delivery system, was used for the rectal infusion of the m odel drug antipyrine. The system, which is sl ightly larger than a norm al suppository ,
https://www.pharmatutor.org/articles/discussion-novel-rectal-drug-delivery-systems-recent-review
· The drug causing severe nausea & vomiting, the oral administration may cause emesis,in that case rectal drug delivery system is helpful, · Irritation to stomach & small intestine associated with certain drug can be avoided, in that case rectal drug delivery system …
https://clinicalgate.com/rectal-and-vaginal-drug-delivery/
• Rectal and vaginal routes are used for local as well as systemic drug delivery and offer some unique advantages. • Both routes have a use in systemic drug delivery when the oral route is not available. • These routes are relatively less popular because of their anogenital nature and privacy aspects.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215502/
Feb 07, 2010 · Introduction. Targeted drug delivery into the colon is highly desirable for local treatment of a variety of bowel diseases such as ulcerative colitis, Crohn’s disease, amebiosis, colonic cancer, local treatment of colonic pathologies, and systemic delivery of protein and peptide drugs.1, 2 The colon specific drug delivery system (CDDS) should be capable of protecting the drug en route to the ...Author: Anil K. Philip, Betty Philip
http://globalresearchonline.net/journalcontents/v21-1/13.pdf
dosage form and drug absorption can be easily interrupted in cases of accidental overdose or suicide attempts. Drug which traditionally is only given parentally may be administered rectally. These advantages for rectal dosing require devices or formulations with specific features to give the desired drug delivery system.File Size: 359KB
http://www.authorstream.com/Presentation/chinmayeechinni-1521280-colon-drug-delivery-system/
Aug 29, 2012 · COLON DRUG DELIVERY SYSTEM - authorSTREAM Presentation. Gastro intestinal transit time.: Gastro intestinal transit time. The arrival of oral dosage form at the colon is determined by the rate of gastric emptying & small intestinal transit time.
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