Protein Therapeutic Delivery

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DELIVERY OF THERAPEUTIC PROTEINS - PubMed Central (PMC)

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857543/
    When compared to the small molecule drugs, therapeutic proteins and peptides need special formulation strategies to become viable therapeutic protein products. As discussed above, various forms of micro/nanoparticulate drug delivery systems have been explored for …Author: Dipak S. Pisal, Matthew P. Kosloski, Sathy V. Balu-Iyer

Basics and recent advances in peptide and protein drug ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956587/
    While the peptide and protein therapeutic market has developed significantly in the past decades, delivery has limited their use. Although oral delivery is preferred, most are currently delivered intravenously or subcutaneously due to degradation and limited absorption in the gastrointestinal tract.Author: Benjamin J Bruno, Geoffrey D Miller, Carol S Lim

Protein based therapeutic delivery agents: Contemporary ...

    https://www.sciencedirect.com/science/article/pii/S0142961217302740
    Herein, we review current strategies employing proteins to facilitate the delivery of therapeutic matter for small molecules, nucleic acids, protein therapeutics, and cells ().As demonstrated, these classes of therapeutics span a variety of clinical applications, and are restricted in their efficacy and/or application due to challenges in delivery.Author: Liming Yin, Carlo Yuvienco, Jin Kim Montclare

Therapeutic Protein - an overview ScienceDirect Topics

    https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/therapeutic-protein
    Christine Dufès, in Peptide and Protein Delivery, 2011. Therapeutic proteins and peptides have been identified as showing great promise for the treatment of brain cancers and neurodegenerative diseases. However, their delivery to their intended site of action from the blood is hampered by the presence of the blood-brain barrier (BBB), a vital element in the regulation of the internal ...

Therapeutic Delivery - Future Science

    https://www.future-science.com/loi/tde
    Therapeutic Delivery welcomes unsolicited article proposals. Email us today to discuss the suitability of your research and our options for authors, including our …

Silica-based nanoparticles for therapeutic protein delivery

    https://pubs.rsc.org/en/content/articlelanding/2017/tb/c7tb00244k
    Nowadays, protein therapeutics receive unprecedented recognition for their great potential in the treatment of a variety of diseases. The efficacy of native therapeutic proteins is limited by their intrinsic poor stability and cell membrane permeability. Tremendous efforts have been devoted to developing efficient protein delivery systems.Author: Meihua Yu, Zhengying Gu, Thomas Ottewell, Thomas Ottewell, Chengzhong Yu

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