Protein Transduction Domain Delivery Of Therapeutic Macromolecules

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Protein transduction domain delivery of therapeutic ...

    https://www.ncbi.nlm.nih.gov/pubmed/21489777
    However, therapeutic use of macromolecules is limited by their poor penetration in tissues and their inability to cross the cellular membrane. The discovery of small cationic peptides that cross the membrane, called Protein Transduction Domains (PTDs) or Cell Penetrating Peptides (CPPs), in the late 1980s opened the door to cellular delivery of large, bioactive molecules.Author: van den Berg A, Dowdy Sf

Protein transduction domain delivery of therapeutic ...

    https://www.sciencedirect.com/science/article/pii/S0958166911000607
    Protein transduction domain delivery of therapeutic macromolecules. Owing to their unprecedented selectivity, specific activity and potential for 1000+ fold amplification of signal, macromolecules, such as peptides, catalytic protein domains, complete proteins, and oligonucleotides, offer great potential as therapeutic molecules.Author: van den Berg A, Dowdy Sf

Protein transduction domain delivery of therapeutic ...

    https://www.sciencedirect.com/science/article/abs/pii/S0958166911000607
    Protein transduction domain delivery of therapeutic macromolecules. Owing to their unprecedented selectivity, specific activity and potential for 1000+ fold amplification of signal, macromolecules, such as peptides, catalytic protein domains, complete proteins, and oligonucleotides, offer great potential as therapeutic molecules.Author: van den Berg A, Dowdy Sf

Protein transduction domain delivery of therapeutic ...

    https://www.researchgate.net/publication/51048216_Protein_transduction_domain_delivery_of_therapeutic_macromolecules
    Protein transduction domains (PTDs) facilitate the delivery of molecules including proteins into cells or tissues. Thus, PTDs were widely used as a tool to investigate the effect of target ...

Protein transduction domain-mediated delivery of ...

    https://mdanderson.elsevierpure.com/en/publications/protein-transduction-domain-mediated-delivery-of-anticancer-prote
    title = "Protein transduction domain-mediated delivery of anticancer proteins", abstract = "Advances in molecular and cellular biological techniques and genomic information obtained through the human genome project have been accelerating the elucidation of the molecular mechanisms underlying cancer.Author: Hiroshi Harada, Masahiro Hiraoka

Organelle-Targeted Delivery of Biological Macromolecules ...

    https://www.sciencedirect.com/science/article/pii/S0022283608006281
    Extensive effort is currently being expended on the innovative design and engineering of new molecular carrier systems for the organelle-targeted delivery of biological cargoes (e.g., peptide aptamers or biological proteins) as tools in cell biology and for developing novel therapeutic approaches.Author: Tomoaki Yoshikawa, Toshiki Sugita, Yohei Mukai, Natsue Yamanada, Kazuya Nagano, Hiromi Nabeshi, Yasu...

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