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http://www.pharmtech.com/pulmonary-drug-delivery-particle-engineering-inhaled-therapeutics
Feb 02, 2014 · For DPI and pMDI suspension products, these formulations must also maintain physical stability of the fine particles and their delivery from the device. Hovione: Pulmonary drug delivery is achieved through an understanding of the complex relationship between particle engineering, formulation and device. There are many goals for a formulation ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334339/
Feb 12, 2015 · Inhalation drug delivery devices: technology update. ... sucrose, sorbitol, glucose) of larger sizes (40 μm).56 Particle engineering approaches are also employed to produce particles using different core materials and more recently of only pure drug ... which can be airflow shear or particle–particle, particle–device impaction. The ...Author: Mariam Ibrahim, Rahul Verma, Lucila Garcia-Contreras
https://www.researchgate.net/publication/294697115_Particle_and_device_engineering_for_inhalation_drug_delivery
The present review is intended to provide a critical account of the current goals and technologies of particle engineering for the development of pulmonary drug delivery systems.
https://www.ondrugdelivery.com/overview-dry-powder-inhalation-systemic-drug-delivery/
J Aerosol Med Pulm Drug Del, 2011, Vol 24(4), pp 175-182. Shoyele SA, Sivadas N, Cryan SA, “The effects of excipients and particle engineering on the biophysical stability and aerosol performance of parathyroid hormone (1-34) prepared as a dry powder for inhalation”. AAPS PharmSciTech, 2011, Vol …
http://www.pharmtech.com/inhalation-drug-delivery-impact-particle-size-reduction
Sep 02, 2019 · RICHARD - STOCK.ADOBE.COM Within the past few years, much has been learned about characterizing the particles used in inhalation therapies, with the goal of improving drug delivery to the lungs. Optimizing the manufacturing of these therapies requires avoiding particle interactions during size reducing, blending, and capsule filling, because these can affect the final product’s quality.
https://www.meddeviceonline.com/doc/what-s-next-in-inhalation-drug-delivery-0001
Jan 10, 2017 · In fact, inhalation delivery is a three-part system consisting of the user, the device, and the drug. Most drugs delivered by inhalation are meant to be inhaled deeply into the lungs, requiring particle sizes of less than 5 microns (μm) and proper aerosolization of the drug. Modification to either device design or drug formulation, or ...
https://www.researchgate.net/publication/272842961_Inhalation_drug_delivery_devices_Technology_update
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386009/
Mar 31, 2015 · The 21st century has seen a paradigm shift to inhaled therapy, for both systemic and local drug delivery, due to the lung's favourable properties of a large surface area and high permeability. Pulmonary drug delivery possesses many advantages, including ...Author: Ibrahim M. El-Sherbiny, Nancy M. El-Baz, Magdi H. Yacoub
https://biotechpharmasummit.com/index.php/event/inhalation-respiratory-drug-delivery-2019/
On 30 & 31 May 2019, New York (USA) will host the BioTech Pharma Summit: Inhalation & Respiratory Drug Delivery 2019 conference. This year’s event is designed for senior industry experts that will showcase new trends in aerosol science and the future directions of inhalation drug delivery research.
https://www.capsugel.com/biopharmaceutical-technologies/inhalation-technology
Capsugel® offers an inhalation drug-delivery approach based on proven particle engineering through spray-drying technology and specialized encapsulation technology, as well as specially designed capsules for use with dry-powder inhalation (DPI) devices.
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