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https://www.sciencedirect.com/science/article/abs/pii/S177322471250081X
The oral delivery of chemotherapeutics could greatly change the common practice of using intravenous injections and ultimately provide improved patient care, comfort, reduction in healthcare costs, and reduction in side effects.Author: C. A. Schoener, Nicholas Peppas
https://www.dovepress.com/advancements-in-the-oral-delivery-of-docetaxel-challenges-current-stat-peer-reviewed-fulltext-article-IJN
Abstract: The oral delivery of cancer chemotherapeutic drugs is challenging due to low bioavailability, gastrointestinal side effects, first-pass metabolism and P-glycoprotein efflux pumps. Thus, chemotherapeutic drugs, including Docetaxel, are administered via an intravenous route, which poses many disadvantages of its own.Author: Muhammad Farhan Sohail, Mubashar Rehman, Hafiz Shoaib Sarwar, Sara Naveed, Omer Salman, Nadeem Irfan...
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.391.9329
The oral delivery of chemotherapeutics could greatly change the common practice of using intravenous injections and ultimately provide improved patient care, comfort, reduction in healthcare costs, and reduction in side effects.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619027/
New delivery methods, particular the oral delivery of chemotherapeutics, could make a dramatic impact to the medical community who administers the cancer treatments and the patients who endure the effects of the cancer treatments. 1–3 Oral chemotherapy has been discussed and presented in the past as systems where chemotherapeutics are delivered to the upper small intestine for subsequent …Author: Cody A. Schoener, Heather N. Hutson, Nicholas A. Peppas
https://onlinelibrary.wiley.com/doi/full/10.1002/adma.201502697
The sacrificial shell protects the core layer with the drugs and prevents their release in the severe pH conditions of the gastrointestinal tract, while allowing for drug release in the proximity of a tumor. The proposed nanoparticulate drug‐delivery system is designed for the oral administration of cancer therapeutics.Author: Mohammad Mahdi Hasani-Sadrabadi, Shahrouz Taranejoo, Erfan Dashtimoghadam, Ghasem Bahlakeh, Fatemeh ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014516/
Oral chemotherapy has distinct advantages and disadvantages compared with intravenous chemotherapy. Although the responsibility for safe handling and administration of oral chemotherapy ultimately lies with the patient or their caregiver, it is the responsibility of all members of the health care team to ensure they are informed regarding the safe and appropriate use of their chemotherapy.Author: Susan Goodin, Niesha Griffith, Beth Chen, Karen Chuk, Mikael Daouphars, Christian Doreau, Rinku A. P...
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