Ocular Delivery System For Acyclovir

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Ocular drug delivery systems: An overview

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289909/
    CONVENTIONAL OCULAR DRUG DELIVERY SYSTEMS. Topical drop instillation into the lower precorneal pocket is a patient compliant and widely recommended route of drug administration. However, most of the topically administered dose is lost due to reflux blinking and only 20% (−7 μL) of instilled dose is retained in the precorneal pocket . Concentration of drug available in the precorneal area acts as a …Author: Ashaben Patel, Kishore Cholkar, Vibhuti Agrahari, Ashim K Mitra

Acyclovir-loaded chitosan nanoparticles for ocular ...

    http://www.asiapharmaceutics.info/index.php/ajp/article/download/290/235
    a material with a good potential for ocular drug delivery. viral diseases owing to poor ocular drug bioavailability. nanosphere colloidal suspension containing acyclovir as potential ophthalmic drug delivery system. chitosan nanoparticles were prepared by ionic gelation of chitosan with tripolyphosphate anions.Author: Rajendran N N, Natrajan R, Siva Kumar R, Selvaraj S

Characterization and In‐vivo Ocular Absorption of Liposome ...

    https://www.onlinelibrary.wiley.com/doi/10.1211/0022357991772664
    The most suitable ophthalmic drug delivery system was oligolamellar systems made up of dipalmitoylphosphatidylcholine—cholesterol—dimethyldioctadecyl glycerole bromide (7:4:1 molar ratio), which presented the highest encapsulation capacity and were able to deliver greater amounts of the drug into the aqueous humour than a saline acyclovir solution or a physical liposome/drug blend.Author: Massimo Fresta, Anna Maria Panico, Claudio Bucolo, Claudia Giannavola, Giovanni Puglisi

OCULAR DRUG DELIVERY: A REVIEW INTERNATIONAL JOURNAL …

    http://ijpsr.com/bft-article/ocular-drug-delivery-a-review/?view=fulltext
    Recent technological advancement has changed the field of ocular drug delivery from conventional drops to sustained release and targeted ocular delivery systems. In the recent era of technology, combinatorial approach seems to be a focus of research in the development of safe and efficient ophthalmic drug delivery systems.

Controlled release polymeric ocular delivery of acyclovir

    https://www.researchgate.net/profile/Nayanabhirama_Udupa/publication/26829728_Controlled_release_polymeric_ocular_delivery_of_acyclovir/links/00b4952e7e0fe8d3a0000000/Controlled-release-polymeric-ocular-delivery-of-acyclovir.pdf
    Controlled release polymeric ocular delivery of acyclovir 373 32 ± 0.5°C with 25 oscillations per minute. One mL of the drug releasing media was withdrawn at various time intervals of 1, 2, 4, 8, 12, 16 and 20 h and replaced by the same volume of the buffer. These samples were filtered through 0.45 μm …

Acyclovir delivery systems Request PDF

    https://www.researchgate.net/publication/23443683_Acyclovir_delivery_systems
    Several biodegradable drug delivery systems have been proposed to enhance the ocular bioavailability of acyclovir, such as permeation enhancers, liposomes [61], and microparticles [62]. SLN ...

Ophthalmic Drug Delivery Systems : An Update

    https://www.djo.org.in/articles/22/2/ophthalmic-drug-delivery.html
    Sep 25, 2013 · For ocular drugs, to be effective ideal drug delivery systems (DDS) should provide the drug at the receptor site of the ocular tissue in relatively higher concentrations to elicit the desired pharmacological response.[1]Author: Biswas Nr

Topical Ocular Drug Delivery: Recent Developments and ...

    https://www.liebertpub.com/doi/10.1089/jop.1986.2.67
    The design of ocular drug delivery systems is undergoing a gradual transition from an empirical to a rational base. This is partly due to a better understanding of the constraints on drug disposition in the eye and partly due to improved approaches in animal and clinical assessment of ocular drugs and drug delivery systems.Author: Vincent H.L. Lee, Joseph R. Robinson

Development of thermosensitive in situ gel nanoemulsions ...

    https://www.sciencedirect.com/science/article/pii/S1773224719303090
    The aim of the current study was to formulate thermosensitive in situ gel nanoemulsions (NEs) containing acyclovir (ACV) for ocular drug delivery and evaluate their ex vivo corneal permeation ability and ocular irritation possibility. ACV loaded NEs were prepared by low energy method.Author: Mohammad Mehdi Mahboobian, Mojdeh Mohammadi, Zahra Mansouri

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