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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289909/
conventional ocular drug delivery systems Topical drop instillation into the lower precorneal pocket is a patient compliant and widely recommended route of drug administration. However, most of the topically administered dose is lost due to reflux blinking and only 20% (−7 μL) of instilled dose is retained in the precorneal pocket [ 8 ] .Author: Ashaben Patel, Kishore Cholkar, Vibhuti Agrahari, Ashim K Mitra
https://www.allfordrugs.com/ocular-drug-delivery-systems-an-overview/
Ocular iontophoresis offers a drug delivery system that is fast, painless and safe; and in most cases, it results in the delivery of a high concentration of the drug to a specific site. Increased incidence of bacterial keratitis, frequently resulting in corneal scarring, offers a clinical condition that may benefit from drug delivery by iontophoresis.
https://www.ncbi.nlm.nih.gov/pubmed/25590022
In the past two decades, ocular drug delivery research acceleratedly advanced towards developing a novel, safe and patient compliant formulation and drug delivery devices/techniques, which may surpass these barriers and maintain drug levels in tissues.Author: Ashaben Patel, Kishore Cholkar, Vibhuti Agrahari, Ashim K Mitra
http://ijpsr.com/bft-article/ocular-drug-delivery-system-an-overview/?view=fulltext
In ocular drug delivery system there are two types of barriers static and dynamic barrier. Static barriers consist of different segment of eye such as cornea, sclera, retina and blood- retinal barriers. In other way dynamic barriers consists choroidal and conjunctival blood flow, lymphatic clearance,...
https://www.nature.com/articles/s41433-020-0809-0
Feb 18, 2020 · Extended ocular drug delivery systems for the anterior and posterior segments: biomaterial options and applications. Expert Opin Drug Deliv 2017;14:611–20. CASAuthor: Jennifer J. Kang-Mieler, Kayla M. Rudeen, Wenqiang Liu, William F. Mieler
https://study.com/academy/lesson/ocular-drug-delivery-systems-medications.html
There are many examples of ocular or eye-based, drug delivery systems and medications. Remember, oculus means eyes. A common way by which drugs can be delivered to the eyes include topical...
https://www.sciencedirect.com/science/article/pii/S1359644618303994
Ocular drugs are usually delivered locally to the eye. Required drug loading, release rate, and ocular retention time of drug delivery systems depend on the potency, bioavailability, and clearance of the drug at the target site.Author: Astrid Subrizi, Astrid Subrizi, Eva M. del Amo, Viktor Korzhikov-Vlakh, Tatiana Tennikova, Marika Ru...
https://www.sciencedirect.com/science/article/abs/pii/0169409X9500016Z
The need for an ocular drug delivery system which has the convenience of a drop, but will localize and maintain drug activity at its site of action, is apparent. Liposomes offer …Author: Dale Meisner, Michael Mezei
https://www.slideshare.net/sagarsavale1/ocular-drug-delivery-system-odds-62796410
Jun 07, 2016 · “The Novel approach of drug delivery system in which drug can Instilled on the cull de sac cavity of eye is known has Ocular drug delivery system”. cull de sac cavity: the space between eye lids and eye balls. The most commonly employed ophthalmic dosage forms are solutions, suspensions, and ointments.
https://www.researchgate.net/publication/225897418_OCULAR_DRUG_DELIVERY_SYSTEM_-_A_REVIEW
Ocular disposition and elimination of a therapeutic agent is dependent upon its physicochemical properties as well as the relevant ocular anatomy and physiology. A successful design of a drug delivery system, therefore, requires an integrated knowledge of the drug …
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