Novel Nanoparticles For Oral Insulin Delivery Via The Paracellular Pathway

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Novel nanoparticles for oral insulin delivery via the ...

    https://iopscience.iop.org/article/10.1088/0957-4484/18/10/105102
    Feb 06, 2007 · In the study, a novel NP system, composed of hydrophilic CS and poly-γ-glutamic acid (γ-PGA), was prepared for oral insulin delivery via the paracellular pathway. γ-PGA, an anionic peptide, is a natural compound produced as a capsular substance or as slime by members of …Author: Yu-Hsin Lin, Chiung-Tong Chen, Hsiang-Fa Liang, Anandrao R Kulkarni, Po-Wei Lee, Chun-Hung Chen, Hsi...

Novel nanoparticles for oral insulin delivery via the ...

    https://www.researchgate.net/publication/229091102_Novel_nanoparticles_for_oral_insulin_delivery_via_the_paracellular_pathway
    Request PDF Novel nanoparticles for oral insulin delivery via the paracellular pathway Novel nanoparticles (NPs) coated with chitosan which allow insulin to be administered orally were developed.

Novel nanoparticles for oral insulin delivery via the ...

    https://iopscience.iop.org/article/10.1088/0957-4484/18/10/105102/meta
    Feb 06, 2007 · Novel nanoparticles for oral insulin delivery via the paracellular pathway. Yu-Hsin Lin 1, Chiung-Tong Chen 2, Hsiang-Fa Liang 1, Anandrao R Kulkarni 1, Po-Wei Lee 1, Chun-Hung Chen 1 and Hsing-Wen Sung 1,3. Published 6 February 2007 • IOP Publishing Ltd …Author: Yu-Hsin Lin, Chiung-Tong Chen, Hsiang-Fa Liang, Anandrao R Kulkarni, Po-Wei Lee, Chun-Hung Chen, Hsi...

Novel nanoparticles for oral insulin delivery via the ...

    https://ui.adsabs.harvard.edu/abs/2007Nanot..18j5102L/abstract
    Mar 01, 2007 · Novel nanoparticles (NPs) coated with chitosan which allow insulin to be administered orally were developed. The NPs could transiently and reversibly open the tight junctions in Caco-2 cell monolayers, thus increasing their paracellular permeability. After oral administration of the FITC-labelled NPs, fluorescence signals, co-localized with ZO-1 proteins, were observed at cell-cell contact ...Author: Yu-Hsin Lin, Chiung-Tong Chen, Hsiang-Fa Liang, Anandrao R Kulkarni, Po-Wei Lee, Chun-Hung Chen, Hsi...

Novel nanoparticles for oral insulin delivery via the ...

    http://adsabs.harvard.edu/abs/2007Nanot..18j5102L
    Novel nanoparticles for oral insulin delivery via the paracellular pathway: Authors: Lin, Yu-Hsin; ... Novel nanoparticles (NPs) coated with chitosan which allow insulin to be administered orally were developed. ... Oral administration of insulin in the form of NPs in diabetic rats demonstrated a sustained effect of decreasing the blood glucose ...

Nanoparticle based insulin delivery system: the next ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619439/
    Oct 24, 2015 · At this juncture, researchers are trying to develop different insulin delivery systems, especially through oral and pulmonary route using nanocarrier based delivery system. This next generation efficient therapy for T1DM may help to improve the quality of life of diabetic patients who routinely employ insulin by the subcutaneous route.Author: Garima Sharma, Garima Sharma, Ashish Ranjan Sharma, Ju-Suk Nam, George Priya C. Doss, Sang-Soo Lee, ...

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