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https://www.sciencedirect.com/science/article/pii/S1549963408000889
We describe the use of methoxypolyethylene glycol–poly(lactide-co-glycolide) nanoparticles as a delivery system for recombinant hepatitis B surface antigen (HBsAg). Evaluation of the stability and release kinetics of nanoencapsulated HBsAg in vitro in serum revealed an initial burst effect and a subsequent slower release of the antigen.Author: Dhruba J. Bharali, Vandana Pradhan, Galina Elkin, Wu Qi, Alan Hutson, Shaker A. Mousa, Yasmin Thanav...
https://www.ncbi.nlm.nih.gov/pubmed/18640075
We describe the use of methoxypolyethylene glycol-poly(lactide-co-glycolide) nanoparticles as a delivery system for recombinant hepatitis B surface antigen (HBsAg). Evaluation of the stability and release kinetics of nanoencapsulated HBsAg in vitro in serum revealed an initial burst effect and a subsequent slower release of the antigen.Author: Dhruba J. Bharali, Vandana Pradhan, Galina Elkin, Wu Qi, Alan Hutson, Shaker A. Mousa, Yasmin Thanav...
https://www.sciencedirect.com/science/article/abs/pii/S1549963408000889
We describe the use of methoxypolyethylene glycol–poly(lactide-co-glycolide) nanoparticles as a delivery system for recombinant hepatitis B surface antigen (HBsAg). Evaluation of the stability and release kinetics of nanoencapsulated HBsAg in vitro in serum revealed an initial burst effect and a subsequent slower release of the antigen.Author: Dhruba J. Bharali, Vandana Pradhan, Galina Elkin, Wu Qi, Alan Hutson, Shaker A. Mousa, Yasmin Thanav...
https://www.researchgate.net/publication/51414215_Novel_nanoparticles_for_the_delivery_of_recombinant_hepatitis_B_vaccine
We describe the use of methoxypolyethylene glycol-poly(lactide-co-glycolide) nanoparticles as a delivery system for recombinant hepatitis B surface antigen (HBsAg).
https://www.sciencedirect.com/science/article/pii/S1773224717303751
In this study, recombinant hepatitis B virus surface antigen (rHBsAg) was loaded in mannosylated chitosan (MC) nanoparticles to be used as a targeted vaccine delivery vehicles. The nanoparticles were prepared by ionic gelation method and characterized for physicochemical properties, cytotoxicity …Author: Mohsen Mehrabi, Naser Mohammadpour Dounighi, Seyed Mahdi Rezayat, Seyed Mahdi Rezayat, Delaram Dorou...
https://www.researchgate.net/publication/324139394_Novel_approach_to_improve_vaccine_immunogenicity_Mannosylated_chitosan_nanoparticles_loaded_with_recombinant_hepatitis_B_antigen_as_a_targeted_vaccine_delivery_system
Novel approach to improve vaccine immunogenicity: Mannosylated chitosan nanoparticles loaded with recombinant hepatitis B antigen as a targeted vaccine delivery system
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468175/
Apr 08, 2019 · Delivery is an important issue, because the majority of vaccines used currently are still administered with a hypodermic needle, either intramuscularly (e.g. hepatitis B or inactivated poliomyelitis), subcutaneously (e.g. measles or yellow fever) or intradermally [e.g. bacillus Calmette–Guérin (BCG)].Author: J. Wallis, D. P. Shenton, R. C. Carlisle
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607064/
Mar 25, 2013 · Classically, ISCOMs have been used to entrap viral envelope proteins such as from herpes simplex virus type 1, hepatitis B, and influenza.Author: Anthony E. Gregory, Richard Titball, Diane Williamson
http://publications.waset.org/5089/chitosan-nanoparticle-as-a-novel-delivery-system-for-ah1n1-influenza-vaccine-safe-property-and-immunogenicity-in-mice
Chitosan Nanoparticle as a Novel Delivery System for A/H1n1 Influenza Vaccine: Safe Property and Immunogenicity in Mice Authors: Nguyen Anh Dzung , Nguyen Thi Ngoc Hà , Dang Thi Hong Van , Nguyen Thi Lan Phuong , Nguyen Thi Nhu Quynh , Dinh Minh Hiep , Le Van Hiep
https://www.researchgate.net/publication/321959391_Development_and_physicochemical_toxicity_and_immunogenicity_assessments_of_recombinant_hepatitis_B_surface_antigen_rHBsAg_entrapped_in_chitosan_and_mannosylated_chitosan_nanoparticles_as_a_novel_vacci
In this study chitosan nanoparticles (CS NPs) and mannosylated chitosan nanoparticles (MCH NPs) loaded with recombinant hepatitis B surface antigen (rHBsAg) was synthesized as a vaccine delivery system and assessed toxically and immunologically.
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