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https://www.sciencedirect.com/science/article/pii/S1549963408000889
We describe the use of methoxypolyethylene glycol–poly(lactide-co-glycolide) nanoparticles as a delivery system for recombinant hepatitis B surface antigen (HBsAg). Evaluation of the stability and release kinetics of nanoencapsulated HBsAg in vitro in serum revealed an initial burst effect and a subsequent slower release of the antigen.Author: Dhruba J. Bharali, Vandana Pradhan, Galina Elkin, Wu Qi, Alan Hutson, Shaker A. Mousa, Yasmin Thanav...
https://www.ncbi.nlm.nih.gov/pubmed/18640075
We describe the use of methoxypolyethylene glycol-poly(lactide-co-glycolide) nanoparticles as a delivery system for recombinant hepatitis B surface antigen (HBsAg). Evaluation of the stability and release kinetics of nanoencapsulated HBsAg in vitro in serum revealed an initial burst effect and a subsequent slower release of the antigen.Author: Dhruba J. Bharali, Vandana Pradhan, Galina Elkin, Wu Qi, Alan Hutson, Shaker A. Mousa, Yasmin Thanav...
https://www.sciencedirect.com/science/article/abs/pii/S1549963408000889
We describe the use of methoxypolyethylene glycol–poly(lactide-co-glycolide) nanoparticles as a delivery system for recombinant hepatitis B surface antigen (HBsAg). Evaluation of the stability and release kinetics of nanoencapsulated HBsAg in vitro in serum revealed an initial burst effect and a subsequent slower release of the antigen.Author: Dhruba J. Bharali, Vandana Pradhan, Galina Elkin, Wu Qi, Alan Hutson, Shaker A. Mousa, Yasmin Thanav...
https://www.researchgate.net/publication/51414215_Novel_nanoparticles_for_the_delivery_of_recombinant_hepatitis_B_vaccine
We describe the use of methoxypolyethylene glycol-poly(lactide-co-glycolide) nanoparticles as a delivery system for recombinant hepatitis B surface antigen (HBsAg).
https://www.sciencedirect.com/science/article/pii/S1773224717303751
In this study, recombinant hepatitis B virus surface antigen (rHBsAg) was loaded in mannosylated chitosan (MC) nanoparticles to be used as a targeted vaccine delivery vehicles. The nanoparticles were prepared by ionic gelation method and characterized for …Author: Mohsen Mehrabi, Naser Mohammadpour Dounighi, Seyed Mahdi Rezayat, Seyed Mahdi Rezayat, Delaram Dorou...
https://www.sciencedirect.com/science/article/abs/pii/S1773224717303751
Novel approach to improve vaccine immunogenicity: Mannosylated chitosan nanoparticles loaded with recombinant hepatitis B antigen as a targeted vaccine delivery systemAuthor: Mohsen Mehrabi, Naser Mohammadpour Dounighi, Seyed Mahdi Rezayat, Seyed Mahdi Rezayat, Delaram Dorou...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468175/
Apr 08, 2019 · The first VLP vaccine to be brought to market was the vaccine for hepatitis B (Recombivax HB), in 1986, which consists of self‐assembled particles made from the virus capsid protein, hepatitis B surface antigen 21.Author: J. Wallis, D. P. Shenton, R. C. Carlisle
https://miami.pure.elsevier.com/en/publications/novel-perspectives-on-the-hepatitis-b-virus-vaccine-in-the-chroni
Dec 01, 2015 · Fabrizi, F, Martin, P & Messa, P 2015, ' Novel perspectives on the hepatitis B virus vaccine in the chronic kidney disease population ', International …Author: Fabrizio Fabrizi, Paul Martin, Piergiorgio Messa
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607064/
Mar 25, 2013 · Nanoparticles as vaccine delivery vehicles Traditional vaccines include live attenuated microbes, killed microbes, or components of microbes. Although many of these vaccines have been central to the control of infectious disease, some do not afford good protection against disease.Author: Anthony E. Gregory, Richard Titball, Diane Williamson
https://www.researchgate.net/publication/321959391_Development_and_physicochemical_toxicity_and_immunogenicity_assessments_of_recombinant_hepatitis_B_surface_antigen_rHBsAg_entrapped_in_chitosan_and_mannosylated_chitosan_nanoparticles_as_a_novel_vacci
In this study chitosan nanoparticles (CS NPs) and mannosylated chitosan nanoparticles (MCH NPs) loaded with recombinant hepatitis B surface antigen (rHBsAg) was synthesized as a vaccine delivery system and assessed toxically and immunologically.
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