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https://www.researchgate.net/publication/317824521_Novel_Mucoadhesive_Polymers_for_Nasal_Drug_Delivery
The mucoadhesive drug delivery system is a popular novel drug delivery method because mucous membranes are relatively permeable, allowing for the rapid uptake of a drug into the systemic ...
https://www.intechopen.com/books/recent-advances-in-novel-drug-carrier-systems/novel-mucoadhesive-polymers-for-nasal-drug-delivery
Novel Mucoadhesive Polymers for Nasal Drug Delivery 1. Introduction. The use of nasal cavity as a route of administration of drugs,... 2. Lectins. Lectins are classified as a group of structurally diverse proteins [ 10]... 3. Thiomers. Thiomers are mucoadhesive polymers that have side chains ...Author: Utkarshini Anand, Tiam Feridooni, Remigius U. Agu
https://cdn.intechopen.com/pdfs/40266/InTech-Novel_mucoadhesive_polymers_for_nasal_drug_delivery.pdf
Novel Mucoadhesive Polymers for Nasal Drug Delivery 319 Factors like low ciliary irritation and high permeability among other considerations favour the potential use of lectins for nasal drug delivery [18]. Studies in animals concluded that lectins have minimal acute irritancy and can be thus be used for further in vivo studies[19].
https://www.semanticscholar.org/paper/Novel-Mucoadhesive-Polymers-for-Nasal-Drug-Delivery-Anand-Feridooni/7bb9bd750e825ce61426f92d0a1bb3db4973e273
The use of nasal cavity as a route of administration of drugs, specifically systemically acting drugs that pose a delivery challenge, have become an area of great interest to the pharmaceutical companies in the past decade. The physiology of the nasal cavity allows for variety of drug delivery possibilities and destinations which include local, systemic, vaccine, and access to the central ...
https://www.researchgate.net/publication/240095823_Novel_Mucoadhesive_Polymers_for_Nasal_Drug_Delivery
We use cookies to offer you a better experience, personalize content, tailor advertising, provide social media features, and better understand the use of our services.Author: Utkarshini Anand
https://www.sciencedirect.com/science/article/pii/S0378517316311188
Jan 30, 2017 · The resulting conjugate was characterized with respect to the amount of coupled ligand, the in situ gelling behavior, mucoadhesive properties and stability towards oxidation. Furthermore, the influence of preactivated polymers on ciliary beat frequency (CBF) of porcine nasal epithelial cells was investigated.Author: Claudia Menzel, Max Jelkmann, Flavia Laffleur, Andreas Bernkop-Schnürch
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255357/
The polymer chains penetrating into the tissue crevices can hold back the ciliary movement, which will increase the retention time of the drugs in the nasal cavity. Furthermore, the existence of the mucoadhesive carrier also reduces the contact between the drugs and the enzymes existing in the mucosa.
http://www.bioline.org.br/pdf?pr08029
drug release properties. The derivatization of the primary amino groups of chitosan with coupling. reagents bearing thiol functions leads to the formation of thiolated chitosans. Various properties of. chitosan are improved by the immobilization of thiol groups.Author: SA Sreenivas, KV Pai
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