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https://www.intechopen.com/books/gene-therapy-tools-and-potential-applications/non-viral-delivery-systems-in-gene-therapy
The main limitation of non-viral systems is their low transfection efficiency, although it has been improved by different strategies and the efforts are still ongoing ; actually, advances of non-viral delivery have lead to an increased number of products entering into clinical trials. However, viral vector has dominated the clinical trials in gene therapy for its relatively high delivery efficiency.Author: Alicia Rodríguez Gascón, Ana del Pozo-Rodríguez, María Ángeles Solinís
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507026/
Jul 06, 2012 · Keywords: Chemical delivery, gene therapy, non viral delivery systems, physical delivery, viral delivery systems INTRODUCTION Basically gene therapy is an intracellular delivery of genomic materials (transgene) into specific cells to generate a therapeutic effect by correcting an existing abnormality or providing the cells with a new function.[ 1 ]
https://www.researchgate.net/publication/233841223_Viral_and_nonviral_delivery_systems_for_gene_delivery
Although numerous viral and nonviral gene delivery systems have been developed in the last 3 decades, no delivery system has been designed that can be applied in gene therapy of all kinds of cell ...
https://www.slideshare.net/Aparajitha_Anne/gene-delivery-system
May 19, 2012 · Inorganic Nanoparticles:It one of the non-viral gene delivery system where we use gold .silicaand iron oxide and calcium phosphate some of the benefits are storagestability, low manufacturing cost and often time, low immunogenicity.
https://www.intechopen.com/books/recent-advances-in-novel-drug-carrier-systems/gene-delivery-systems-recent-progress-in-viral-and-non-viral-therapy
Non-viral gene delivery systems were introduced as an alternative to viral-based systems. One of the most important advantages of these systems is improved transfection. Non-viral systems are categorized according to preparation, as physical or chemical types.Author: Erdal Cevher, Ali Demir Sezer, Emre Şefik Çağlar
https://www.powershow.com/viewfl/1b3e4f-ZDc1Z/Gene_Delivery_powerpoint_ppt_presentation
Gene therapy - A normal gene may be inserted into a nonspecific location within the genome to ... are the tumour cells and cells of the vasculature supplying blood to the tumour, ... PowerPoint PPT presentation free to view.
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