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https://www.ondrugdelivery.com/wp-content/uploads/2018/11/Nov2005.pdf
NASAL DELIVERY TECHNOLOGY: ANATOMY + INNOVATIVE DEVICE = ADDED VALUE OPPORTUNITY Direct-Haler A/S has invented and developed a novel nasal delivery device and nasal delivery principle. The innovation takes advantage of the patient’s anatomy to improve nasal delivery effectiveness and convenience.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539067/
Oct 18, 2012 · Nasal delivery is the logical choice for topical treatment of local diseases in the nose and paranasal sinuses such as allergic and non-allergic rhinitis and sinusitis. The nose is also considered an attractive route for needle-free vaccination and for systemic drug delivery, especially when rapid absorption and effect are desired.Author: Per Gisle Djupesland
https://www.optinose.com/exhalation-delivery-systems/nasal-delivery-challenges
Optinose Exhalation Delivery Systems use a unique Bi-Directional™ mechanism of action designed to reliably and effectively deliver medications or vaccines high and deep throughout the nasal passages. References [1] Djupesland PG. Nasal drug delivery devices: characteristics and performance in a clinical perspective—a review.
http://www.intranasal.net/PainControl/Pain_Control_overview.htm
Key Concepts regarding delivery of any nasal medication to the systemic circulation and brain Use the right dose! Nasal medication doses are NOT equivalent to IV dosing. Using an IV dose will usually fail. (Read about bioavailability in the Overview page) A general rule of thumb is you will need twice the IV dose (often times more).
http://intranasal.net/DeliveryTechniques/default.htm
A second method of intranasal drug delivery is to take a solubilized medication (liquid form) and drip it into the nose a few drops at a time, allowing it to run down onto the nasal mucosa. This can be done using a syringe or in some instances using the packaged form of the medication …
https://www.3m.com/3M/en_US/drug-delivery-systems-us/technologies/nasal/
Your patients deserve better nasal drug delivery than aqueous nasal sprays for allergic rhinitis. These sprays can drip down the throat and out of the nose, causing irritation, embarrassment, and unpleasant aftertastes. 3M can help deliver your treatments with intuitive patient-friendly nasal MDIs.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161189/
Aug 03, 2018 · In general, the nasal cavity is highly suitable for drug delivery as the nasal mucosa presents an efficient absorption and a very good permeability of both: small molecule drugs and biopharmaceuticals. Furthermore, the roof of the nasal cavity is located in very close vicinity to the brain (skull base) and harbours nerves that project to the ...Author: Stella Gänger, Katharina Schindowski
https://www.drugs.com/condition/nasal-congestion.html
76 rows · Alternative treatments for Nasal Congestion. The following products are considered to be …
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