Non-Viral Gene Delivery Methods

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Non-viral gene delivery methods.

    https://www.ncbi.nlm.nih.gov/pubmed/23437936
    Non-viral approaches show high potential due to advantages of relative safety, ability to transfer large size gene, less toxicity and easiness for preparation etc. However, the clinical application of non-viral methods is still restricted by some limitations including low …Author: Weiwei Wang, Wenzhong Li, Nan Ma, Gustav Steinhoff

Viral and nonviral delivery systems for gene delivery

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507026/
    Jul 06, 2012 · Physical methods of nonviral gene delivery. Physical methods applied for in vitro and in vivo gene delivery are based on making transient penetration in cell membrane by mechanical, electrical, ultrasonic, hydrodynamic, or laser-based energy so that DNA entrance into the targeted cells is facilitated.

Non-Viral Delivery Systems in Gene Therapy IntechOpen

    https://www.intechopen.com/books/gene-therapy-tools-and-potential-applications/non-viral-delivery-systems-in-gene-therapy
    Non-Viral Delivery Systems in Gene Therapy. ... Since the initial studies, hundreds of cationic lipids have been synthesized as candidates for non-viral gene delivery and a few made it to clinical trials [85,86]. ... 3.3. Physical methods for gene delivery.Author: Alicia Rodríguez Gascón, Ana del Pozo-Rodríguez, María Ángeles Solinís

Non-Viral Gene Delivery Methods Bentham Science

    http://www.eurekaselect.com/106191/article
    In order to improve gene transfer efficacy, a lot of efforts have been made in the past years, and numerous gene carriers and techniques have been developed. In this review, we summarized the features, drawbacks and prospects of existing and emerging non-viral gene delivery methods.

Non-viral gene delivery systems for tissue repair and ...

    https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-018-1402-1
    Feb 15, 2018 · One of the current state-of-the-art methods for TRR is gene therapy. Non-viral gene delivery systems (nVGDS) have great potential for TE and have several advantages over viral delivery including lower immunogenicity and toxicity, better cell specificity, better …Author: Pan Wu, Haojiao Chen, Ronghua Jin, Tingting Weng, Jon Kee Ho, Chuangang You, Liping Zhang, Xingang W...

Non‐viral gene delivery for cancer immunotherapy - Wang ...

    https://onlinelibrary.wiley.com/doi/abs/10.1002/jgm.3092
    A brief overview is provided of the recent advances in the non‐viral gene delivery methods that are being used to activate cancer‐specific immune responses. Furthermore, the tumor microenvironment‐responsive synergistic strategies that modulate the immune response by targeting various signaling pathways are discussed.Author: Weiqi Wang, Weiqi Wang, Madiha Saeed, Yao Zhou, Lili Yang, Dangge Wang, Haijun Yu

Non-viral gene therapy: Gains and challenges of non ...

    https://www.sciencedirect.com/science/article/pii/S0168365915302649
    An overview of non-viral gene delivery tools for non-systemic administration. A) Nucleic acids (DNA, therapeutic oligonucleotides and gene editing) and bio- and nanotechnology tools, including ex vivo methods, used in non-viral gene therapy. B) Schematic diagram of the building blocks, delivery systems and non-invasive administration routes in ...Author: Marianna Foldvari, Ding Wen Chen, Nafiseh Nafissi, Daniella Calderon, Lokesh Narsineni, Amirreza Raf...

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