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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617524/
An appropriate drug/gene delivery system that can sustain and deliver therapeutics to the target tissues and cells is a key need for ocular therapies. The application of nanotechnology in medicine is undergoing rapid progress, and the recent developments in nanomedicine-based therapeutic approaches may bring significant benefits to address the ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289909/
To overcome the ocular drug delivery barriers and improve ocular bioavailability, various conventional and novel drug delivery systems have been developed such as emulsion, ointments, suspensions, aqueous gels, nanomicelles, nanoparticles, liposomes, dendrimers, implants, contact lenses, nanosuspensions, microneedles, and in situ ...Author: Ashaben Patel, Kishore Cholkar, Vibhuti Agrahari, Ashim K Mitra
https://www.sciencedirect.com/science/article/pii/S0378517317308724
Topically-applied dosage forms, such eye drops, are the most used formulations in the treatment of ocular diseases. Nonetheless, because of the special protection of the eye associated with the ocular surface, drug bioavailability and subsequent therapeutic efficiency obtained with these conventional dosage forms are very low.Author: Jesus Alvarez-Trabado, Jesus Alvarez-Trabado, Yolanda Diebold, Yolanda Diebold, Alejandro Sanchez
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0392-8
Sep 19, 2018 · The use of ideal nano-drug delivery system is decided primarily based on the biophysical and biochemical properties of the targeted drugs being selected for the treatment . However, problems such as toxicity exhibited by nanoparticles cannot be ignored when considering the use of nanomedicine.Author: Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto, Leonardo Fernandes Fraceto, Estefani...
https://www.researchgate.net/publication/337165845_Application_of_nanoparticles_in_ocular_drug_delivery_systems
Application of a drug in the form of eye drops represents easiest, safest and, at the moment, the most common non-invasive method of ocular drug application.
https://www.researchgate.net/publication/279418971_Microparticles_and_Nanoparticles_in_Ocular_Drug_Delivery
Microparticles and Nanoparticles in Ocular Drug Delivery 457 Fig. 5 In vitro release profiles of piroxicam microspheres M1 and M2 compared to the dissolution profile of micronized piroxicam powder.
https://www.sciencedirect.com/topics/nursing-and-health-professions/drug-delivery-system
Drug Delivery System. A drug delivery system (DDS) is defined as a formulation or a device that enables the introduction of a therapeutic substance into the body and improves its efficacy and safety by controlling the rate, time, and place of release of drugs in the body.
https://link.springer.com/article/10.1007%2Fs12553-019-00381-w
Nov 11, 2019 · Application of a drug in the form of eye drops represents easiest, safest and, at the moment, the most common non-invasive method of ocular drug application. Other conventional ophthalmic formulations in the form of aqueous and oily solutions, ointments, suspensions and emulsions were established to increase bioavailability, solubility and pericorneal retention time of a drug, …Author: Naida Omerović, Edina Vranić
https://www.slideshare.net/patelbindi/nanoparticle-37752067
Aug 07, 2014 · Enhance immune response Poly methyl metha acrylate nanoparticles with vaccines DNA delivery Enhanced bioavailability and significantly higher expression level DNA gelatin nanoparticles, DNA chitosan nanoparticles Ocular delivery Improved retention of the drug and reduced washed out.
https://www.tandfonline.com/doi/pdf/10.3109/10717544.2010.483257
employed for ocular drug delivery and yielded some promising results. Solid lipid nanoparticles (SLNs) have been looked at as a potential drug carrier system since the 1990s. SLNs do not show biotoxicity as they are prepared from physiological lipids. SLNs are especially useful in …
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