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https://www.tandfonline.com/doi/abs/10.1080/17425247.2019.1610384?needAccess=true
(2019). Oral delivery of nanoparticles - let’s not forget about the protein corona. Expert Opinion on Drug Delivery: Vol. 16, No. 6, pp. 563-566.
https://link.springer.com/content/pdf/10.1208%2Fs12249-019-1325-z.pdf
Nanoparticles: Oral Delivery for Protein and Peptide Drugs ... BARRIERS TO ORAL DELIVERY OF PROTEIN AND PEPTIDE DRUG NPS Most of the protein and peptide drugs are macromolec-ular hydrophilic, in the extreme environment of gastrointes-tinal stability, susceptible to gastric acid and pepsin
https://www.researchgate.net/publication/325236677_Nanoparticle-Based_Oral_Drug_Delivery_Systems_Targeting_the_Colon_for_Treatment_of_Ulcerative_Colitis
Key W ords: IBD therapy, ulcera tive colitis, nanoparticles, oral drug delivery systems. INTRODUCTION. In ammatory bowel disease (IBD) is a gr oup of chronic .
https://en.wikipedia.org/wiki/Solid_lipid_nanoparticle
Use for drug delivery. Solid lipid nanoparticles have recently materialized as a novel approach to oral and parenteral drug delivery systems.SLNs combine the advantages of lipid emulsion and polymeric nanoparticle systems while overcoming the temporal and in vivo stability issues that troubles the conventional as well as polymeric nanoparticles drug delivery approaches (Mehnert et al., 2001).
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0392-8
The green chemistry route of designing nanoparticles loaded with drugs is widely encouraged as it minimises the hazardous constituents in the biosynthetic process. Thus, using green nanoparticles for drug delivery can lessen the side-effects of the medications . Moreover, adjustments in nanostructures size, shape, hydrophobicity, and surface ...
https://pubs.acs.org/doi/10.1021/acsami.9b00152
The goal of this study was to develop bioadhesive food protein nanoparticles using zein (Z), a hydrophobic corn protein, as the core and whey protein (WP) as the shell for oral pediatric drug delivery applications. Lopinavir (LPV), an antiretroviral drug, and fenretinide, an investigational anticancer agent, were used as model drugs in the study.
https://pubs.rsc.org/en/content/articlelanding/2017/nr/c7nr05762h
The oral pathway is considered as the most common method for drug administration, although many drugs, especially the highly pH- and/or enzymatic biodegradable peptide drugs, are very difficult to formulate and achieve a good intestinal absorption. Efficient systematic absorption of an active substance, deli Recent Review Articles
https://www.cd-bioparticles.com/t/Drug-Delivery_51.html
Nanoparticle drug carriers can shield drugs from degradation and deliver them to intended sites within the gastrointestinal tract and enable more efficient and sustained drug delivery. The most well-known application of nanoparticles in oral delivery is the oral administration of insulin.
https://www.nature.com/articles/s41551-019-0465-5
Anionic nanoparticles increase intestinal permeability and enable the oral delivery of proteins, as shown with the delivery of insulin in healthy, hyperglycaemic, and diabetic mice.
https://cen.acs.org/pharmaceuticals/drug-delivery/Nanoparticles-enable-oral-insulin-delivery/97/web/2019/11
Drug Delivery Nanoparticles enable oral insulin delivery in mice The particles help insulin, a peptide, to slip through the intestinal wall and into the bloodstream by Megha Satyanarayana
https://link.springer.com/article/10.1208/s12249-019-1325-z
May 20, 2019 · Protein nanocrystallization is a new kind of oral drug delivery system. Protein nanoparticles with a particle size of 50–500 nm are formed by crystallization technology, and stable nanoparticles are formed by charge or space stabilization of surfactants.
https://www.hindawi.com/journals/jdd/2012/750891/
Lipids and lipid nanoparticles are extensively employed as oral-delivery systems for drugs and other active ingredients. These have been exploited for many features in the field of pharmaceutical technology. Lipids usually enhance drug absorption in the gastrointestinal tract (GIT), and when formulated as nanoparticles, these molecules improve mucosal adhesion due to small particle size …
https://www.atsjournals.org/doi/full/10.1164/rccm.200504-613PP
Nanoparticle-based drug delivery systems have considerable potential for treatment of tuberculosis (TB). The important technological advantages of nanoparticles used as drug carriers are high stability, high carrier capacity, feasibility of incorporation of both hydrophilic and hydrophobic substances, and feasibility of variable routes of administration, including oral application and inhalation.
https://www.nature.com/articles/s41392-017-0004-3
Mar 16, 2018 · Nanocarriers for drug delivery. Nanomedicine is a rapidly developing area that is revolutionizing cancer diagnosis and therapy. Nanoparticles have …
https://www.understandingnano.com/nanotechnology-drug-delivery.html
Perhaps the most publicized use of nanotechnology in drug delivery under development is the use of nanoparticles to deliver drugs to cancer cells. Particles are engineered so that they are attracted to diseased cells, which allows direct treatment of those cells.
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