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https://www.nature.com/articles/s41573-019-0012-9
Feb 01, 2019 · Adeno-associated virus (AAV) vectors represent the leading platform for therapeutic gene delivery, with two recombinant AAV gene therapy products having …Author: Dan Wang, Phillip W. L. Tai, Guangping Gao
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687232/
Nov 27, 2012 · The viral gene delivery systems include lytic and nonlytic vectors for drug delivery. Inspite of its toxicity they are still preferred because of their long term expression, stability, and integrity. This review explores the recent developments and relevancy …
https://www.ncbi.nlm.nih.gov/pubmed/32125904
Mar 11, 2020 · In addition, we compare the characteristics and differences of current drug delivery systems and expound the principles of selecting a drug delivery system suitable for cancer gene therapy.Expert opinion: EVs are highly biocompatible membrane structures with low cytotoxicity which provide a new choice for drug delivery in RNA-based cancer gene ...Author: Vivian Weiwen Xue, Vivian Weiwen Xue, Sze Chuen Cesar Wong, Guoqi Song, William Chi Shing Cho
https://www.nejm.org/doi/full/10.1056/NEJM199511023331808
Gene therapy is a novel form of drug delivery that enlists the synthetic machinery of the patient's cells to produce a therapeutic agent. Using the body to treat its own disease overcomes the need ...Author: Helen M. Blau, Matthew L. Springer
https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(00)90040-6
Mar 01, 2000 · It is also true that gene therapy has been held–rightly or wrongly— to be separate and special. However, the development of gene delivery shares many more similarities with drug development than it does differences. Gene therapy must be developed in the same way as for any other drug.Author: Barrie J. Carter
https://bme.duke.edu/research/drug-gene-delivery
Important areas in this growing field include development of delivery vehicles such as plasmids, nanoparticles, viruses, liposomes, peptide/protein complexes, and biomaterial scaffolds, as well as studies of drug and gene transport, delivery strategies, delivery barriers, and …
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