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https://www.ncbi.nlm.nih.gov/pubmed/20875340
Gene therapy for cancer: dairy bacteria as delivery vectors. Tangney M(1). ... agents upon administration to tumors and promising clinical trial successes have been achieved with various types of gene delivery vehicles. Bacteria present an attractive class of gene vectors, possessing a natural ability to grow specifically within tumors ...Author: Tangney M
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056088/
Furthermore, invasive species can deliver heterologous genes intra-cellularly for tumor cell expression. Here, we review the use of bacteria as vehicles for gene therapy of cancer, detailing the mechanisms of action and successes at preclinical and clinical levels.
https://reference.medscape.com/medline/abstract/20875340
Gene therapy for cancer: dairy bacteria as delivery vectors. Discov Med. 2010; 10(52):195-200 (ISSN: 1944-7930) Tangney M. The prime obstacle to achieving an effective treatment for cancer is that of eradicating tumors without harming healthy organs and cells of the patient.
https://www.nature.com/articles/cgt201259
Sep 21, 2012 · The attractiveness of bacteria as vectors for cancer gene therapy is evidenced by the growing number and range of studies that have employed bacteria. ... Gene therapy for cancer: dairy bacteria ...Author: M Cronin, R M Stanton, K P Francis, M Tangney
https://www.researchgate.net/publication/316012241_Gene_therapy_using_bacterial_vectors
Jan 01, 2017 · Gene therapy using bacterial vectors. ... alternative gene therapy is suitable for in situ delivery of proteins and treatment with intracellular bactochondria. A specific form of bacteria-mediated ...
https://www.researchgate.net/publication/46580685_Bacterial_vectors_and_delivery_systems_in_cancer_therapy
Bacterial vectors and delivery systems in cancer therapy Gardlik & Fruehauf 703 703 ( A ) Auxotrophic bacteria specifi cally colonize tumors with necrotic and hypoxic ar eas.
http://www.nature.com/articles/cgt201716
Jun 02, 2017 · New methods in the diagnosis of cancer and gene therapy of cancer based on nanoparticles ... Gene therapy for cancer: dairy bacteria as delivery vectors. ... New methods in the diagnosis of cancer ...Author: M A Zaimy, N Saffarzadeh, A Mohammadi, H Pourghadamyari, P Izadi, A Sarli, L K Moghaddam, S R Pasche...
http://www.genetherapynet.com/viral-vectors.html
The concept of gene therapy seems straightforward, but this is clearly an oversimplification, and numerous problems and risks exist that prevent gene therapy using viral vectors. Viruses can usually infect more than one type of cell.
https://microbialcellfactories.biomedcentral.com/articles/10.1186/s12934-015-0383-5
Dec 12, 2015 · However, a combination of the prodrug CB1954 and a strain expressing a secreted chromate reductase effectively inhibited MCTS growth. Collectively, the presented results indicate that MCTS are a suitable and reliable model to investigate live bacteria as …Author: Annika Osswald, Annika Osswald, Zhongke Sun, Verena Grimm, Grace Ampem, Karin Riegel, Astrid M. West...
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