Molecular Aptamers For Drug Delivery

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Molecular aptamers for drug delivery

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218254/
    The cell membrane is basically a dynamic lipid bilayer; therefore, this liposome nanostructure can efficiently increase cell permeability and enhance drug delivery. A cell-permeable sgc8-PEG-liposome nanostructure has also been reported for drug delivery . With approximately 250 aptamers on each liposome, this design leads to multiple aptamer-receptor interactions, provides better binding to the …Author: Weihong Tan, Weihong Tan, Hui Wang, Yan Chen, Yan Chen, Yan Chen, Xiaobing Zhang, Haizhen Zhu, Chaoy...

Molecular aptamers for drug delivery - ScienceDirect

    https://www.sciencedirect.com/science/article/pii/S0167779911001132
    The ability of DNA or RNA aptamers to act as targeting agents enables these molecules to be conjugated with therapeutic agents for use in targeted drug delivery. Early diagnosis of disease relies not only on the specificity of the molecular probes but also on the detection sensitivity.Author: Weihong Tan, Weihong Tan, Hui Wang, Yan Chen, Yan Chen, Yan Chen, Xiaobing Zhang, Haizhen Zhu, Chaoy...

Molecular aptamers for drug delivery - tan.chem.ufl.edu

    https://tan.chem.ufl.edu/wp-content/uploads/sites/39/pubs/important-articles/Molecular%20aptamers%20for%20drug%20delivery.pdf
    Aptamers as delivery agents Aptamers can be designed as targeting ligands, particu- larly when generated by cell-based SELEX, and can dif- ferentiate diseased cells from healthy cells, thus enabling the selective delivery of therapeutic compounds to target cells (Table 1).

Molecular aptamers for drug delivery: Trends in Biotechnology

    https://www.cell.com/trends/biotechnology/references/S0167-7799(11)00113-2
    The ability of DNA or RNA aptamers to act as targeting agents enables these molecules to be conjugated with therapeutic agents for use in targeted drug delivery. Early diagnosis of disease relies not only on the specificity of the molecular probes but also on the detection sensitivity.Author: Weihong Tan, Weihong Tan, Hui Wang, Yan Chen, Yan Chen, Yan Chen, Xiaobing Zhang, Haizhen Zhu, Chaoy...

Molecular aptamers for drug delivery - Europe PMC Article ...

    https://europepmc.org/articles/PMC3218254
    Dec 01, 2011 · The ability of DNA or RNA aptamers to act as targeting agents enables these molecules to be conjugated with therapeutic agents for use in targeted drug delivery. Early diagnosis of disease relies not only on the specificity of the molecular probes, but also on the detection sensitivity.Author: Weihong Tan, Weihong Tan, Hui Wang, Yan Chen, Yan Chen, Yan Chen, Xiaobing Zhang, Haizhen Zhu, Chaoy...

Molecular aptamers for drug delivery Request PDF

    https://www.researchgate.net/publication/51551790_Molecular_aptamers_for_drug_delivery
    When used as nanoparticles, aptamers are a good choice to combat against molecular mechanisms of drug resistance. Surpassing other chemical and molecular probes such as monoclonal antibodies,...

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