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https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/metered-dose-inhaler
Yousef Javadzadeh, Shadi Yaqoubi, in Nanostructures for Drug Delivery, 2017. 6.2 Metered Dose Inhaler (MDI) Metered-dose inhaler is an inhaler device with specified doses that provides a certain dose of the active agent in each puff. MDIs consist of a suspension or dispersion of one or more active ingredient in propellant or a mixture of propellants or a mixture of solvent and propellants, are ...
https://www.nicklauschildrens.org/care-guides/drug-delivery-devices-metered-dose-inhalers-and-s
Drug delivery devices: Metered dose inhalers and spacers The metered dose inhaler (MDI) is the most common device people use to take asthma medication. An MDI allows you to inhale a specific amount of medicine (a "metered dose").
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334339/
Feb 12, 2015 · Pressurized metered-dose inhalers. pMDIs are the most popular inhalers to treat local respiratory diseases such as asthma and COPD. ... Pulmonary drug delivery is an attractive route of administration for diverse entities including micro and macromolecules such as vaccines, DNA, ...Author: Mariam Ibrahim, Rahul Verma, Lucila Garcia-Contreras
https://www.ncbi.nlm.nih.gov/pubmed/32130023
Mar 16, 2020 · For this reason, there are several ongoing technical innovations to improve inhaler devices.Areas covered: Progress in pulmonary drug delivery device technology is examined, focusing on innovations in pressurized metered dose inhalers, dry powder inhalers, nebulizers, and soft mist inhalers.Expert opinion: Both formulation improvements and new ...Author: Mario Cazzola, Francesco Cavalli, Omar S Usmani, Paola Rogliani
https://www.sciencedirect.com/science/article/pii/S0091674995702075
Drug delivery from an MDI results from a complex interaction between the formulation, valve, and actuator. Several factors contribute to the dose reproducibility of MDIs. Although these factors may be transient and not representative of the average behavior of MDI performance during routine use, such differences may still be of clinical importance.Author: Robert K. Schultz
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