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https://www.sciencedirect.com/science/article/pii/S0378517300003355
Mar 20, 2000 · The incorporation of cyclodextrins into polymeric drug delivery systems can influence the mechanisms by which drug is released. Physically mixed and complexed cyclodextrins for example, can modify drug solubility or diffusivity, improve hydration of the polymer matrix …Author: David C. Bibby, Nigel M. Davies, Ian G. Tucker
https://www.ncbi.nlm.nih.gov/pubmed/10704788
Mar 20, 2000 · Mechanisms by which cyclodextrins modify drug release from polymeric drug delivery systems. Bibby DC(1), Davies NM, Tucker IG. Author information: (1)Formulation and Drug Delivery Group, School of Pharmacy, University of Otago, PO Box 913, Dunedin, New Zealand. [email protected]: David C. Bibby, Nigel M. Davies, Ian G. Tucker
https://www.researchgate.net/publication/12610520_Mechanism_by_which_cyclodextrins_modify_drug_release_from_polymeric_drug_delivery_systems
There are three mechanisms for drug release from polymeric hydrogel systems that are erosion, diff ;usion, and swelling. ...
https://www.sciencedirect.com/science/article/pii/S1773224710500467
Cyclodextrins in drug delivery systems. Cyclodextrins are one of the most versatile aids in pharmaceutical technology, being of interest for the formulation of a wide range of delivery devices from the most classical dosage forms to the newest drug carriers.Author: F.J. Otero-Espinar, J.J. Torres-Labandeira, C. Alvarez-Lorenzo, J. Blanco-Méndez
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147107/
Controlled and targeted drug delivery system. Whereas most of the earlier work done on CDs concentrated o-n their property to enhance the release rate of drugs from dosage forms, some recent work has also been done to evaluate CDs as carriers in controlled release drug delivery systems.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750546/
Oct 14, 2005 · The purpose of this review is to discuss and summarize some of the interesting findings and applications of cyclodextrins (CDs) and their derivatives in different areas of drug delivery, particularly in protein and peptide drug delivery and gene delivery.Author: Rajeswari Challa, Alka Ahuja, Javed Ali, R. K. Khar
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438887/
Since the advent of controlled release polymer drug delivery systems (DDS), the polymer therapeutics field has exploded as the focus has shifted toward strategies that facilitate targeted release, especially for anticancer drugs, which often have severe negative side effects.Author: William B. Liechty, David R. Kryscio, Brandon V. Slaughter, Nicholas A. Peppas
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401754/
Dec 12, 2018 · 3. Mechanism of Drug Release from Implantable Polymeric Drug Delivery Systems. Mechanisms of drug release from implantable systems are mainly classified into four groups: matrix degradation; controlled swelling; osmotic pumping; and passive diffusion . For systems based on controlled swelling, solvent penetration into the matrix of the device ...Author: Sarah A. Stewart, Juan Domínguez-Robles, Ryan F. Donnelly, Eneko Larrañeta
https://www.sciencedirect.com/science/article/pii/S0169409X1400129X
Drug release rate depends on the rate of drug diffusion within the delivery system, the drug partition coefficient, the stability of the micelles and the rate of polymer degradation . The most important mechanism of drug release from liposomes or solid lipid nanoparticles is drug diffusion through the lipid bilayers or lipid matrix.Author: Cristina Loira-Pastoriza, Julie Todoroff, Rita Vanbever
http://www.eurekaselect.com/83262/article/intelligent-drug-delivery-systems-polymeric-micelles-and-hydrogels?tracking-code=4
Advanced drug delivery systems try to adjust the site and/or the rate of the release to the physiological conditions of the patient, to the progression of ...
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