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https://www.researchgate.net/publication/264613524_A_Lysosome_-_Targeted_Drug_Delivery_System_Based_on_Sorbitol_Backbone_towards_Efficient_Cancer_Therapy
A Lysosome - Targeted Drug Delivery System Based on Sorbitol Backbone towards Efficient Cancer Therapy Article (PDF Available) in Organic & Biomolecular Chemistry 12(34) · July 2014 with 717 Reads
https://www.sciencedirect.com/topics/medicine-and-dentistry/lysosome
This drug was once thought to hold value for the field of gene therapy, if only in a laboratory setting. By preventing the acidification of (endo)lysosomes, chloroquine prevents the activation of the associated degradative enzymes and therefore prevents the destruction of gene delivery complexes in …
https://www.sciencedirect.com/science/article/pii/S0169409X12002980
Drug release rates have important implications for the therapeutic activities of all types of drug delivery systems, including liposomes. It is important to keep in mind that drug entrapped in liposomes is not bioavailable; it only becomes bioavailable when it is released.Author: Theresa M. Allen, Pieter R. Cullis
https://www.ncbi.nlm.nih.gov/pubmed/25233432
The natural sphingolipid sphingosine exhibits lysosomotropic detergent ability and is an endogenous candidate for controlling lysosomal membrane permeabilization. The lysosomotropic properties of certain detergents might be of use in lysosome-targeting anticancer drugs and drug delivery system in the future.Author: Ana M. Villamil Giraldo, Hanna Appelqvist, Thomas Ederth, Karin Öllinger
https://www.ncbi.nlm.nih.gov/pubmed/28862054
Lysosomes are of particular interest for the design and delivery of pH-dependent pro-drugs, enhancing selectivity and developing strategies to inhibit drug degradation inside the cells. There is great potential to bring intracellular drug delivery and distribution using nanotherapeutic approaches to target lysosomes for therapeutic interventions.Author: Ankur Sharma, Kalpesh Vaghasiya, Eupa Ray, Rahul Kumar Verma
http://www.authorstream.com/Presentation/phani.thanneru-1598552-drug-delivery-lysosomal-storage-diseases/
Drug Delivery to Lysosomal Storage Diseases - authorSTREAM Presentation. Slide 18: Enzyme Delivery across the Blood-Brain Barrier(BBB): 1.BBB is characterized by a layer endothelial cells, joined by tight junction 2. this restricts transport of bulk recombinant enzymes across brain Methods used to by pass the barrier are 1 .opening BBB by infusion of hypo osmotic solution (arabinose) into the ...
https://www.tandfonline.com/doi/abs/10.1080/1061186X.2017.1374390
Sep 21, 2017 · AbstractLysosomes are of particular interest for the design and delivery of pH-dependent pro-drugs, enhancing selectivity and developing strategies to inhibit drug degradation inside the cells. There is great potential to bring intracellular drug delivery and distribution using nanotherapeutic approaches to target lysosomes for therapeutic interventions.Author: Ankur Sharma, Kalpesh Vaghasiya, Eupa Ray, Rahul Kumar Verma
https://www.researchgate.net/publication/216045812_Drug_delivery_systems_Advanced_technologies_potentially_applicable_in_personalized_treatments
Advanced drug delivery systems (DDS) present indubitable benefits for drug administration. Over the past three decades, new approaches have been suggested for the development of novel carriers for ...
https://www.omicsonline.org/open-access/liposomes-for-drug-delivery-2155-952X276-97370.html
Drug encapsulation in a liposomal or lipid drug delivery system improves the pharmacokinetic and pharmacodynamic properties to such an extent that the drugs can be brought into regular use . Advantages of liposomes as a drug delivery system for antimicrobials are: • Improvement and control over pharmacokinetics and pharmacodynamicsAuthor: Durgavati Yadav, Kumar Sandeep, Deepak Pandey, Ranu Kumari Dutta
https://www.youtube.com/watch?v=Up0RclkzeOY
May 04, 2017 · This Video describes about how liposomes acts as drug carriers in targeted drug delivery system. This Video describes about how liposomes acts as drug carriers in targeted drug delivery system.Author: Chakka Tharun
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