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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249419/
Thus, the advantages of using nanoparticles for drug delivery are a result of two main basic properties: small size and use of biodegradable materials. Nanoparticles, because of their small size, can extravasate through the endothelium in inflammatory sites, epithelium (e.g., intestinal tract and liver), tumors, or penetrate microcapillaries.Author: Rajesh Singh, James W. Lillard, James W. Lillard
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
A multitude of substances are currently under investigation for the preparation of nanoparticles for drug delivery, varying from biological substances like albumin, gelatine and phospholipids for liposomes, and more substances of a chemical nature like various polymers and solid metal containing nanoparticles.Author: Wim H De Jong, Paul Ja Borm
https://www.understandingnano.com/nanotechnology-drug-delivery.html
Researchers are developing nanoparticles that can delivery drugs across the brain barrier to tackle neurologic disorders. A method being developed to fight aging uses mesoporous nanoparticles with a coating that releases the contents of the nanoparticle when an emzyme found in aging cells is present.
https://drug-dev.com/nanoparticles-a-revolution-in-the-development-of-drug-delivery-vehicles/
ABSTRACT. Nanoparticles, and liposomes in particular, have been used for drug delivery in cancer and inflammatory disease therapies for several years, but traditional manufacturing methods are labor intensive, hard to reproduce, and difficult to scale up.
https://pubs.acs.org/doi/abs/10.1021/acs.iecr.9b04747
Significant efforts have been made to fabricate drug-loaded nanoparticles for drug delivery. Nanoprecipitation is a simple and versatile method for making various types of polymer nanoparticles with well-controlled particle size, size distribution, and surface properties.Author: Yun Liu, Guangze Yang, Da Zou, Yue Hui, Krishna D. P. Nigam, Anton Middelberg, Chun-Xia Zhao
https://www.sciencedirect.com/science/article/pii/S1319016417301792
An ideal nanoparticle drug delivery system should be able to reach, recognized, bind and deliver its load to specific pathologic tissues, and minimize or avoids drug induced damage to healthy tissues.Thus, coating specific targeting ligand(s) on the surface of nanoparticles is the most common strategy.Author: Syed A.A. Rizvi, Ayman M. Saleh
https://www.nih.gov/news-events/nih-research-matters/chemotherapy-using-nanoparticles
The technique involves storing a cancer drug inside tiny objects called nanoparticles. Using this method, researchers were able to shrink tumors in mice while using smaller doses of the drug to reduce harmful side effects. The chemotherapy drug cisplatin is an effective cell killer. It's used against half of all human cancers.
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Other NIBIB-funded researchers are developing a system of drug delivery using a type of bacteria that has a two-part navigation system—magnetic and oxygen sensing. They have tested the delivery system in mice, achieving a remarkable success delivering drugs to …
https://www.sciencedirect.com/science/article/pii/B9780128136898000021
The possible applications are: Nanoscale drugs and targeted drug delivery, antimicrobial medical dressings and textiles, in vivo imaging methods, bone and dental prostheses, and coatings for in vivo implants to support substances for the regeneration of tissues.Author: Deepti Sharma, Navneet Sharma, Mallika Pathak, Paban K. Agrawala, Mitra Basu, Himanshu Ojha
https://innovareacademics.in/journal/ijpps/Vol3Suppl2/965.pdf
In fact protein is biopolymer, which is commonly used for preparation of nano structured molecules for drug delivery. In this articles various techniques have been discussed in detail for the preparation of nanoparticles using natural polymers chitosan,alginate and proteins such as albumin,gelatin,legumin.
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