We have collected information about Intraocular Drug Delivery Implants for you. Follow the links to find out details on Intraocular Drug Delivery Implants.
https://www.assignmentpoint.com/science/medical/intraocular-implants-for-extended-drug-delivery.html
Intraocular implants for drug delivery are capable of bypassing the barriers to intraocular drug absorption and avoid frequent procedures required using intravitreal injection therapy. Drug release rates of implants can be controlled so that therapeutic drug levels are maintained in the eye, while avoiding toxic or subtherapeutic levels.
https://www.sciencedirect.com/science/article/pii/S0169409X06001645
Intraocular implants for extended drug delivery: Therapeutic applications ☆ 1. Introduction. The eye is the organ of choice for the practical implantation or injection... 2. Description of the polymers used for intraocular drug delivery implants. 3. Therapeutic applications of ocular implants. ...Author: J.L. Bourges, C. Bloquel, C. Bloquel, Aurélien Thomas, Aurélien Thomas, F. Froussart, F. Froussart, ...
https://www.ondrugdelivery.com/biodegradable-implants-sustained-intraocular-delivery-small-large-molecules/
EyeLief™ is a preformed implant (Figure 2) that can be administered intraocularly to achieve sustained delivery of a wide range of drug molecules. Being photosensitive, the implant can be selectively crosslinked so as to achieve the desired release rates over an extended period.
https://www.tandfonline.com/doi/abs/10.1517/17425247.3.2.261
Aug 12, 2014 · Drug delivery from ocular implants. Developing an intraocular drug delivery system (DDS) is urgently needed because most vitreoretinal diseases are refractory to conventional pharmacological approaches; eye drops and systemically administered drugs cannot deliver therapeutic drug concentrations into vitreoretinal tissue.Author: Tsutomu Yasukawa, Yuichiro Ogura, Hideya Kimura, Eiji Sakurai, Yasuhiko Tabata
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306122/
Dec 26, 2010 · Intraocular or periocular injections can deliver relatively high doses of drug to the eye with few or no systemic side effects. However, such injections are associated with significant complications and must often be repeated at regular intervals. Compliance with any form of regular medication can be a problem,...Author: Nahid Haghjou, Masoud Soheilian, Mohammad Jafar Abdekhodaie
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000300024
Intraocular implants are controlled drug delivery systems prepared from biodegradable or non-biodegradable polymers. Generally, these are introduced into the vitreous through an incision in the ocular pars plana , which is located posterior to the lens and anterior to the retina.
https://www.ondrugdelivery.com/scalability-micro-intraocular-implants-devices/
Not only is the natural response affected by the chemical properties of the polymer but also by the physical properties of the implant. Development of an ophthalmologic drug delivery device requires design criteria compatible with the delicate nature of the eye, including proper materials, size, shape, and porosity. Material Selection
http://www.mavery.com/academic/Intraocular_DDS.pdf
An intraocular drug deliver system (DDS) refers to a device that is surgically implanted into your eye and then ideally would constantly releases drugs for a set time. This includes both biodegradable and non-biodegradable devices, and the development of
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333484/
The preparation of the implants was performed by a melt-extrusion method. The developed extrudates were characterized and compared in in-vitro release profiles for elucidating the drug release mechanism. The formulations containing up to 40% w/w of drug were prepared.Author: Lana Tamaddon, S Abolfazl Mostafavi, Reza Karkhane, Mohammad Riazi-Esfahani, Farid Abedin Dorkoosh, ...
https://www.webmd.com/eye-health/cataracts/intraocular-lens-implant
An intraocular lens implant is an artificial replacement for the lens of your eye. It's part of the surgery to fix cataracts. How Your Eye Works. Each eye has a lens -- a window made of clear protein and water that sits behind the pupil. The lens focuses light onto the retina, which sends it to your brain.
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