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https://www.researchgate.net/publication/47680681_Intracellular_Delivery_of_Nanoparticles_with_CPPs
Intracellular Delivery of Nanoparticles with CPPs Article in Methods in molecular biology (Clifton, N.J.) 683:431-51 · January 2011 with 15 Reads How we measure 'reads'
https://link.springer.com/protocol/10.1007%2F978-1-60761-919-2_31
Oct 12, 2010 · Cell-penetrating peptides (CPPs), in particular TATp, have been widely used for intracellular delivery of various cargoes, both in vitro and in vivo. Modifications of nanoparticles with CPPs require either covalent or noncovalent approach.Author: Rupa Sawant, Vladimir Torchilin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747576/
In general, CPPs may help (i) to broaden the spectrum of cell types that internalize VPs with a cargo (e.g., with concern to gene therapy); (ii) to increase the efficiency of the intracellular delivery of VPs with a therapeutic payload; (iii) to modulate the interaction of VPs with immune cells (e.g., regarding vaccine development), and (iv) to ...Author: Jana Váňová, Alžběta Hejtmánková, Marie Hubálek Kalbáčová, Hana Španielová
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825215/
Nov 01, 2019 · Peptides and biologics provide unique opportunities to modulate intracellular targets not druggable by conventional small molecules. Most peptides and biologics are fused with cationic uptake moieties or formulated into nanoparticles to facilitate delivery, but these systems typically lack potency due to low uptake and/or entrapment and degradation in endolysosomal compartments.Author: Brian C. Evans, R. Brock Fletcher, Kameron V. Kilchrist, Eric A. Dailing, Alvin J. Mukalel, Juan M. ...
https://pubs.acs.org/doi/pdf/10.1021/acsnano.9b07930
KEYWORDS: intracellular delivery, nanoparticle delivery, macromolecule delivery, cell transfection, hydroporator, hydroporation, inertial microfluidics N anomaterials such as functional nanoparticles and synthetic biomolecules have attracted considerable attention, particularly from the cell biology commun-
http://web.mst.edu/~huangy/Publications/2013_Intracellular%20delivery%20of%20nanoparticles%20and%20DNAs%20by%20IR9%20cell-penetrating%20peptides.pdf
CPPs can deliver cargoes with sizes up to 200 nm in diameter [17]. Our laboratory has used arginine-rich CPPs to deliver proteins [18–26], DNAs [27–33], RNAs [34] and nanoparticles [35–39] into cells from various species. The internalization kinetics of CPPs is rapid, with a first-order rate constant of 0.007 sec21 [40]. CPPs are not toxic
https://pubs.acs.org/doi/10.1021/acsnano.9b07930
Despite efforts to understand the interactions between nanoparticles and cells, the cellular processes that det. the efficiency of intracellular drug delivery remain unclear. Here we examine cellular uptake of short interfering RNA (siRNA) delivered in lipid nanoparticles (LNPs) using cellular trafficking probes in combination with automated ...Author: GeoumYoung Kang, Daniel W. Carlson, Tae Ho Kang, Seungki Lee, Simon J. Haward, Inhee Choi, Amy Q. Sh...
https://www.mdpi.com/1996-1944/12/17/2671/pdf
Intracellular Delivery of Viral Nanoparticles ... provides and describes various examples of and means of exploitation of CPPs in order to enhance the delivery of VPs into permissive cells and/or to allow them to enter a broad range of cell types. Moreover, it is possible that CPPs are capable of changing the immunogenic properties of VPs ...Author: Jana Váňová, Alžběta Hejtmánková, Marie Hubálek Kalbáčová, Hana Španielová
https://www.nature.com/articles/s41467-019-12906-y
Nov 01, 2019 · Sequential delivery of 5 µM PPAA followed by 0.5 or 1 µM YARA-HiBiT peptide significantly enhanced intracellular delivery (Supplementary Fig. 18), …Author: Brian C. Evans, R. Brock Fletcher, Kameron V. Kilchrist, Eric A. Dailing, Alvin J. Mukalel, Juan M. ...
https://www.sciencedirect.com/science/article/pii/S0196978114001314
This review discussed the uptake mechanism and recent advances in the use of CPPs for intracellular delivery of a variety of biomolecules. Use of CPPs for delivery of various nanoparticles and nanocarriers including quantum dot, liposome, nanosilver, polymeric nanoparticle, gold …Author: Samad Mussa Farkhani, Alireza Valizadeh, Hadi Karami, Samane Mohammadi, Nasrin Sohrabi, Fariba Badrz...
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