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https://www.diabetesselfmanagement.com/managing-diabetes/treatment-approaches/ways-deliver-insulin-inhalers-insulin-pumps/
Sep 18, 2019 · Distributed by MannKind, Afrezza is a dry form of a fast-acting insulin. It’s delivered with a small, whistle-shaped device (much more portable than Exubera), and it starts to work within 12 minutes of inhalation. Once Afrezza is inhaled, it passes into the lungs and then into the bloodstream to lower blood glucose.Author: Amy Campbell, MS, RD, LDN, CDE
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787057/
INHALED INSULIN. Insulin delivery to the lungs was the first reported alternate to subcutaneous injection. It has long been appreciated that insulin delivery by aerosol reduces blood glucose.
https://www.webmd.com/diabetes/features/insulin-delivery
Uneven insulin delivery. Because they send insulin into the body through the pores, jet injectors may not always deliver an accurate dose. Other options include an insulin patch. Work closely with your doctor to choose the option that best fits your budget, health needs, and lifestyle.
https://www.touchendocrinology.com/inhaled-insulina-new-insulin-delivery-system/
Given the efficacy and tolerability of inhaled insulin, inhaled insulin is a promising new delivery system that provides prandial insulin coverage, and it may ultimately play an important role in the future management of diabetes.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792528/
Inhalation delivery system for insulin (Exubera ®) is the first alternative method of insulin delivery that has recently been introduced to the market after FDA approval. The product would need time to gain acceptance from other health authorities, to provide long-term safety profile and gain popularity among health care professionals and patients.
https://dlife.com/down-the-inhaled-insulin-path-the-road-to-approval-and-acceptance/
Aug 21, 2018 · Many technical advances since that time have allowed insulin delivery through other means, including insulin pens, pumps and even the possibility of a pill, one day. It wasn’t until the late 1990s that the idea of inhaled insulin actually came to fruition.
Insulin you inhale at the beginning of your meal. Afrezza is the only rapid acting insulin available that can be inhaled. Other mealtime insulin options are delivered through injection. Afrezza can potentially save you about 1,000 needle sticks per year.
https://www.lifeextension.com/Magazine/2015/2/Health-Risks-Of-Inhalation-Insulin-For-Diabetics/
Inhaled insulin affects all tissue it comes in contact with upon delivery, and since insulin induces cell division, this can lead to aberrant cell growth. Hypoglycemia, exacerbation of asthma symptoms, and adverse effects in those with pre-existing respiratory diseases are also areas of concern regarding inhaled insulin.
https://www.webmd.com/diabetes/inhaled-insulin
Inhaled insulin is another option for people with diabetes to control their blood sugar. It works for both type 1 and type 2 diabetes, but you shouldn't use it if you smoke or have asthma or COPD.
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