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https://www.sciencedirect.com/topics/veterinary-science-and-veterinary-medicine/macula-densa
Increased NaCl delivery and its uptake through NKCC-2 in macula densa cells is coupled to the generation of a signal that causes vasoconstriction of the afferent arterioles, which lowers the GFR and returns the distal delivery of NaCl to close to its usual levels. This response is known as tubuloglomerular feedback.
https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/macula-densa-cell
Increased NaCl delivery and its uptake through NKCC-2 in macula densa cells is coupled to the generation of a signal that causes vasoconstriction of the afferent arterioles, which lowers the GFR and returns the distal delivery of NaCl to close to its usual levels. This response is known as tubuloglomerular feedback.
https://www.ncbi.nlm.nih.gov/pubmed/3524919
Crystalline cores were seen in 1.5% and 7% of the granules, respectively. Increased delivery of NaCl to the macula densa did not alter total renin, but decreased inactive renin from 30% to 0, crystalline core-containing cells from 33% to 14% and decreased the percentage …Author: T. Wong, T. O. Morgan, D. Alcorn, G. B. Ryan
https://forums.studentdoctor.net/threads/help-macula-densa-aldosterone-and-lumen-sodium-concentration.898869/
Mar 30, 2012 · hello, i need help ..i want to ask you..i have known for several years that the macula densa senses the lumen chloride and when the lumen sodium is low, then the macula densa will stimulates the release of renin and eventually increase the angiotensin II to further constricts the efferent arteriole and also dilates the afferent arteriole...,visa versa..
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577295/
Macula densa cells in the distal nephron, according to the classic paradigm, are salt sensors that generate paracrine chemical signals in the juxtaglomerular apparatus to control vital kidney functions, including renal blood flow, glomerular filtration, and renin release.Author: János Peti-Peterdi, Raymond C. Harris
https://quizlet.com/10313147/physio-memory-renal-flash-cards/
3. It increases the sensitivity of the tubuloglomerular feedback mechanism (decreases GFR) normally increased NaCl delivery to macula densa (high flow) increases vasoconstriction of afferent- with increased sensitivity less flow still stimulates vasoconstriction 4.
https://quizlet.com/118174373/regulation-of-renal-blood-flow-and-gfr-flash-cards/
Increased NaCl delivery to the macula densa causes release of a vasoconstrictor that constricts the afferent arteriole, lowers Pgc, and decreases GFR 3. A decrease in the rate of flow through the loop of Henle and distal tubule (a sign of reduced GFR) triggers …
https://www.kidney-international.org/article/S0085-2538(15)49471-2/fulltext
We hypothesized that an increase in intracellular Ca ++ at the macula densa is essential for tubuloglomerular feedback and evaluated the source of increased macula densa Ca ++ concentration in response to increased luminal delivery of NaCl…Author: Yilin Ren, Ruisheng Liu, Oscar A. Carretero, Jeffrey L. Garvin
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