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https://www.sciencedirect.com/science/article/pii/S0169409X10001705
Imaging and drug delivery using theranostic nanoparticles ... Some promising applications use nanometer-scale particles for simultaneous drug delivery and molecular imaging. There are unique opportunities to use multifunctional formulations for both diagnostic and therapeutic purposes. This review focuses on the inherent feasibility and ...Author: Siti M. Janib, Ara S. Moses, J. Andrew MacKay
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769170/
Aug 30, 2010 · Dendrimers have been in development for years and have proven to be successful drug and imaging agent carriers in a number of preclinical studies, including, tumor regression, gene delivery, and molecular imaging [6,34,51]. Barriers to address prior to theranostic use of dendrimers include toxicity of the nanoparticle, its polymeric component ...Author: Siti M. Janib, Ara S. Moses, J. Andrew MacKay
https://www.researchgate.net/publication/45649901_Imaging_and_drug_delivery_using_theranostic_nanoparticles
Imaging and drug delivery using theranostic nanoparticles Article · Literature Review (PDF Available) in Advanced drug delivery reviews 62(11):1052-63 · August 2010 with 219 Reads
https://www.sciencedirect.com/science/article/abs/pii/S0169409X10001705
Imaging and drug delivery using theranostic nanoparticles ... Here we review state-of-the-art nanoparticles from a therapeutic and a diagnostic perspective and discuss challenges in bringing these fields together. Major classes of nanoparticles include, drug conjugates and complexes, dendrimers, vesicles, micelles, core–shell particles ...Author: Siti M. Janib, Ara S. Moses, J. Andrew MacKay
https://www.ncbi.nlm.nih.gov/pubmed/30809308
Jan 24, 2019 · The effects of the theranostic nanoparticle on targeted drug delivery, therapeutic efficacy, non-invasive magnetic resonance image (MRI)-guided therapy, and optical imaging detection of therapy resistant tumors were examined in an orthotopic human ovarian cancer xenograft model with highly heterogeneous levels of HER2 expression.
http://www.thno.org/v10p4557.htm
Stimuli-responsive nanocarriers for drug delivery, tumor imaging, therapy and theranostics ... Sato Y, Sakamoto W, Yogo T. Theranostic nanoparticles for MRI-guided thermochemotherapy: “Tight” clustering of magnetic ... pH and near-infrared light dual-stimuli responsive drug delivery using DNA-conjugated gold nanorods for effective ...
https://pubs.acs.org/doi/full/10.1021/ar200106e
Sep 15, 2011 · Nanoparticles (NPs) offer diagnostic and therapeutic capabilities not available with small molecules or microscale tools. As the field of molecular imaging has emerged from the blending of molecular biology with medical imaging, NP imaging is increasingly common for both therapeutic and diagnostic applications. The term theranostic describes technology with concurrent and …Author: Jesse V. Jokerst, Sanjiv S. Gambhir
https://pubs.acs.org/doi/10.1021/mp100298r
The past decade has seen momentous development in brain cancer research in terms of novel imaging-assisted surgeries, molecularly targeted drug-based treatment regimens or adjuvant therapies and in our understanding of molecular footprints of initiation and progression of malignancy. However, mortality due to brain cancer has essentially remained unchanged in the last three decades. Thus ...Author: Mahaveer Swaroop Bhojani, Marcian Van Dort, Alnawaz Rehemtulla, Brian D. Ross
https://www.cancer.gov/nano/research/alliance/ircn/emory
Building upon our understanding of pancreatic cancer biology and expertise in developing theranostic nanoparticles, we are developing a stroma breaking drug delivery system using a new generation of 3-nm ultra-fine magnetic iron oxide nanoparticle (uIONP) coated with an anti-fouling 'stealth' polymer for enhanced tumor penetration and retention ...
http://www.thno.org/v07p1689.htm
Tumor Penetrating Theranostic Nanoparticles for Enhancement of Targeted and Image-guided Drug Delivery into Peritoneal Tumors following Intraperitoneal Delivery . Ning Gao 1*, Erica N. Bozeman 1*, Weiping Qian 1, Liya Wang 2, Hongyu Chen 3, Malgorzata Lipowska 2, Charles A Staley 1, Y. Andrew Wang 3, Hui Mao 2, Lily Yang 1, 2 . 1.Author: Ning Gao, Erica N. Bozeman, Weiping Qian, Liya Wang, Hongyu Chen, Malgorzata Lipowska, Charles A Sta...
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