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https://www.sciencedirect.com/science/article/pii/S0032386108000487
Hydrogels used in drug delivery are usually formed outside of the body and impregnated with drugs before placement of the hydrogel–drug complex in the body. A wide range of cross-linking strategies can be used, including UV photopolymerization and various chemical cross-linking techniques.Author: Todd R. Hoare, Daniel S. Kohane
http://www.orientjchem.org/vol29no3/hydrogels-smart-materials-for-drug-delivery/
Emergence of hydrogels as drug delivery system The word smart polymers originated from the ability of hydrogels to imitate the non-linear response of DNA and Proteins. 11 Above all the characteristic features of hydrogels, their behaviour to adapt structural changes in response to various physical or chemical trigger (Figure 3) and make them intelligent candidates for drug delivery system. The current drug delivery …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438887/
The majority of responsive polymers for drug delivery can be broadly categorized as hydrogels, micelles, polyplexes, or polymer-drug conjugates, which are covered in more detail below. Hydrogels are hydrophilic (co)polymeric networks capable of imbibing large amounts of …Author: William B. Liechty, David R. Kryscio, Brandon V. Slaughter, Nicholas A. Peppas
https://www.hindawi.com/journals/ijps/2019/3160732/
Based on the conductive polymer poly(3-methoxydiphenylamine) and pectin hydrogels, Mongkolkitikul et al. synthesize a drug delivery system to transport ibuprofen. And the study showed that under applied electric potential, the diffusion coefficient of a drug is much higher than those without electric potential due to the mesh size expansion [ 107 ].Author: Ke Wang, Yuting Hao, Yingna Wang, Jinyuan Chen, Lianzhi Mao, Yudi Deng, Junlin Chen, Sijie Yuan, Tia...
https://www.nature.com/articles/natrevmats201671
Oct 18, 2016 · Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery and have found clinical use. Hydrogels can provide spatial and temporal control over the release of various therapeutic agents, including small-molecule drugs, macromolecular drugs and cells.Author: Jianyu Li, David J. Mooney
https://www.youtube.com/watch?v=f2-N_kxHjK4
Jun 28, 2010 · Hydrogels, Micelles, Dendrimers. It comes with its own super glue. Drug delivery systems involve polymer that biodegrades and some form permanent networks which use the hydrogen and oxygen from the...Author: Skizit Gesture
https://pubs.acs.org/doi/10.1021/acsnano.5b01433
Injectable thermosensitive hydrogel systems based on functional PEG/PCL block polymer for local drug delivery. Journal of Controlled Release 2019 , 297 , 60-70. DOI: 10.1016/j.jconrel.2019.01.026.Author: Sonia Merino, Cristina Martín, Kostas Kostarelos, Maurizio Prato, Ester Vázquez
https://www.sciencedirect.com/science/article/pii/S0168365920302108
Apr 02, 2020 · Nanoparticles (NPs), polyspheres and copolymer hydrogels have for instance found a wide range of application as controlled drug delivery system in biomedical research [,,,, ], including also cancer research and photothermal therapy [ 19 ].
https://www.sciencedirect.com/science/article/pii/B9780128140338000035
Thereby, hydrogel nanocomposite properties may affect the release behavior of drugs from the hydrogel network. Once the structure of hydrogel nanocomposites can be a reservoir of molecules, a sustained drug delivery can be developed considering the interaction between the drug and the hydrogel system [4], [31].Author: Débora F. Argenta, Talitha C. dos Santos, Angela M. Campos, Thiago Caon
https://pubs.acs.org/doi/10.1021/acs.biomac.0c00077
The hydrogel dissolved slowly and released the pseudo-block copolymer in the form of micelles that continued to serve as drug carriers with DOX encapsulated in the hydrophobic core, achieving a better cellular uptake and anticancer effect than free DOX controls, even in multidrug-resistant cancer cells.Author: Xia Song, Zhongxing Zhang, Jingling Zhu, Yuting Wen, Feng Zhao, Lijie Lei, Nhan Phan-Thien, Boo Cheo...
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