We have collected information about Gene Delivery To The Brain for you. Follow the links to find out details on Gene Delivery To The Brain.
https://www.ncbi.nlm.nih.gov/pubmed/17406580
Stereotaxic gene delivery in the rodent brain. Cetin A(1), Komai S, Eliava M, Seeburg PH, Osten P. Author information: (1)Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Jahnstrasse 29, 69120 Heidelberg, Germany.Author: Ali Cetin, Shoji Komai, Marina Eliava, Peter H Seeburg, Pavel Osten
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630580/
Routes of gene delivery: the long and winding road. Many studies have been published regarding delivery of genes to the nervous system. Strength of transgene expression and distribution throughout the brain are dependent on vector backbone, promoters used, and site, volume, and rate of injection.5,6 Different vectors, as well as delivery in various stages of brain development, have been used ...Author: Manfred Schubert, Xandra Breakefield, Howard Federoff, Robert M Frederickson, Pedro R Lowenstein
https://www.pnas.org/content/102/4/1211
Jan 25, 2005 · Gene delivery of apoE2 may prevent or reduce brain Aβ burden and the subsequent development of neuritic plaques. Apolipoprotein E (apoE) alleles are important genetic risk factors for Alzheimer's disease (AD), with the ε4 allele increasing and the ε2 allele decreasing risk for developing AD. ... Gene Delivery of Human apoE4 Increases Brain ...Author: Jean-Cosme Dodart, Robert A. Marr, Milla Koistinaho, Beth M. Gregersen, Seema Malkani, Inder M. Verm...
https://www.sciencedirect.com/science/article/pii/S0168365910006668
The lack of worldwide scientific endeavor toward solving the obstacles in brain gene targeting, is quite surprising especially considering its extreme potential in alleviating human suffering. Therefore to address the impending research foray, the work should contribute significant insight into the gene delivery to …Author: Sejin Son, Do Won Hwang, Kaushik Singha, Ji Hoon Jeong, Tae Gwan Park, Dong Soo Lee, Won Jong Kim
https://n.neurology.org/content/62/8/1275
Apr 27, 2004 · Gene therapy offers the promise of an effective cure for both genetic and acquired brain disease. However, the limiting problem in brain gene therapy is delivery to brain followed by regulation of the expression of the transgene. Present day gene vectors do not cross the blood-brain barrier (BBB).Author: Felix Schlachetzki, Yun Zhang, Ruben J. Boado, William M. Pardridge
https://www.statnews.com/2016/02/02/virus-blood-brain-barrier-genes/
A method using viruses may be able to deliver therapeutic genes to the brain. Above, green fluorescent protein (GFP) is shown in the mouse cerebellum after the GFP gene is delivered using the method.
https://www.researchgate.net/publication/6414530_Stereotaxic_gene_delivery_in_the_rodent_brain
Stereotaxic gene delivery in the rodent brain. ... gene delivery by recombinant adeno-associated viruses and lentiviruses in mice and rats. This method allows the manipulation of gene expression ...
https://www.pnas.org/content/102/32/11539
Aug 09, 2005 · Gene delivery into the brain ventricular space has an advantage of minimizing damage of the brain tissue and could potentially allow expression of the transgenes in several brain structures that surround the ventricles and in cells within the ventricular wall.Author: Dhruba J. Bharali, Ilona Klejbor, Ewa K. Stachowiak, Purnendu Dutta, Indrajit Roy, Navjot Kaur, Earl...
Searching for Gene Delivery To The Brain?
You can just click the links above. The data is collected for you.
