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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053525/
Drug delivery across the mucosa bypasses the first-pass hepatic metabolism and avoiding the degradation of gastrointestinal enzymes. Thus mucosal drug delivery system could be of value in delivering a growing number of high-molecular-weight sensitive …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255397/
Mucoadhesive drug delivery systems interact with the mucus layer covering the mucosal epithelial surface, and mucin molecules and increase the residence time of the dosage form at the site of absorption. The drugs which have local action or those which have maximum absorption in gastrointestinal tract (GIT) require increased duration of stay in GIT.
http://ijpsr.com/bft-article/a-detailed-review-on-oral-mucosal-drug-delivery-system/?view=fulltext
INTRODUCTION: Oral mucosal drug delivery system is subdivided into buccal and sublingual in which buccal cavity is widely applicable for drug administration through mucosa in case of sublingual route mostly useful for fastest onset of action as in the case of Angina pectoris. The buccal mucosa lines the inner cheek, and buccal formulations are placed in the mouth between the upper gingivae (gums) and …
https://www.mdpi.com/journal/pharmaceutics/special_issues/mucoadhesive_mucosal_DDS
Mucosal drug delivery is designed to target drugs to mucosal membranes covering the respiratory tract, the eye, the female genital tract, and the gastrointestinal tract. Mucosal drug delivery is suitable for local drug administration to treat mucosal diseases as well as for systemic drug distribution.
https://www.researchgate.net/publication/46818092_MUCOSAL_DRUG_DELIVERY_SYSTEM
The attractiveness of mucosal-targeted controlled drug delivery of active pharmaceutical ingredients, has led formulation scientists to evaluate numerous polymeric systems for such tasks.
https://www.slideshare.net/sayedasalma/evaluation-of-buccal-drug-delivery-system
Feb 02, 2018 · BUCCAL BIOADHESIVE PATCHES AND FILMS • Buccal bioadhesive patches consists of two poly- laminates or multilayered thin film round or oval ,consisting of basically a bioadhesive polymeric layer and impermeable backing layer to …
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