Gene Delivery To The Hair Follicle

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Gene Delivery to the Hair Follicle - ScienceDirect

    https://www.sciencedirect.com/science/article/pii/S0022202X15529679
    Gene therapy of the hair follicle is at an early stage of investigation, but these studies clearly demonstrate that genes could be delivered to hair follicles directly in vivo and during ex vivo culture, providing a theoretical basis for hair follicle gene therapy. We also now know how topical gene delivery is optimally performed during early ...Author: Manabu Ohyama, Jonathan C. Vogel

Gene Delivery to the Hair Follicle - ResearchGate

    https://www.researchgate.net/publication/9036224_Gene_Delivery_to_the_Hair_Follicle
    Gene Delivery to the Hair Follicle Article in Journal of Investigative Dermatology Symposium Proceedings 8(2):204-6 · November 2003 with 18 Reads How we measure 'reads'

Gene delivery to the hair follicle — Keio University

    https://keio.pure.elsevier.com/en/publications/gene-delivery-to-the-hair-follicle
    Oct 01, 2003 · T1 - Gene delivery to the hair follicle. AU - Ohyama, Manabu. AU - Vogel, Jonathan C. PY - 2003/10. Y1 - 2003/10. N2 - Skin and appendages such as hair follicles are attractive candidates for gene therapy targets because they are easily accessible and can be removed and genetically manipulated in culture.Author: Manabu Ohyama, Jonathan C. Vogel

Gene Delivery to the Hair Follicle

    https://www.jidsponline.org/article/S0022-202X(15)52967-9/pdf
    gene delivery to hair follicles and discuss examples of how gene delivery can cause phenotypic changes in hair follicles. Key words: hair follicle/gene therapy/hair cycle/ anagen. JID Symposium Proceedings 8:204^206, 2003 TTHERAPEUTIC USES OF GENE DELIVERY here are two major reasons for introducing genes into hair follicles for therapeutic ...

Efficient delivery of transgenes to human hair follicle ...

    https://www.nature.com/articles/nbt0400_420
    Apr 01, 2000 · The topical delivery of transgenes to hair follicles is an attractive approach for treating disorders of the skin and hair. The hair follicle contains epithelial stem cells, which cyclically ...Author: Alevtina Domashenko, Sonya Gupta, George Cotsarelis

Hair-GEL, searchable Gene Expression Library for hair ...

    http://hair-gel.net/
    Hair-GEL. searchable Gene Expression Library for hair follicles. Rendl ... Mok KW, Heitman NJ, Clavel C, Ma'ayan A, Rendl M (2015) An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, their Niche and the Developing Skin. Developmental Cell doi:10.1016 ... Transit-Amplifying Progenitors, and their Niche in Developing Hair ...

Drug Targeting to the Hair Follicles: A Cyclodextrin-Based ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663695/
    INTRODUCTION. Topical drug delivery systems that selectively target hair follicles and sweat glands are of interest to both the pharmaceutical and the cosmetic industry not only to treat dermal complications but also for systemic drug delivery (1,2).Possible dermal applications include treatment of acne, inflammation, and hair growth disorders.Author: Fífa Konrádsdóttir, Helga Ogmundsdóttir, Valgardur Sigurdsson, Thorsteinn Loftsson

The feasibility of targeted selective gene therapy of the ...

    https://www.nature.com/articles/nm0795-705
    Jul 01, 1995 · That liposomes can target the hair follicle for delivery has been confirmed independently7. Two decades ago we introduced the technique of entrapping DNA in liposomes for use in gene therapy8 ...Author: Lingna Li, Robert M. Hoffman

Follicular Drug Delivery: a Root to Success

    https://themedicinemaker.com/discovery-development/follicular-drug-delivery-a-root-to-success
    L Li, RM Hoffman, “The feasibility of targeted selective gene therapy of the hair follicle”, Nat Med, 1, 705–706 (1995). A Domashenko, S Gupta, GC Cotsarelis, “Efficient delivery of transgenes to human hair follicle progenitor cells using topical lipoplex”, Nat Biotech, 18, 420–423 (2000).

How to deliver DNA specifically to hair follicles in Gene ...

    https://www.researchgate.net/post/How_to_deliver_DNA_specifically_to_hair_follicles_in_Gene_Therapy
    The hair follicle is a readily accessible mini organ within the skin and contains stem cells from diverse developmental origins that are shown to have surprisingly broad differentiation potential ...

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