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http://www.eurekaselect.com/109082/article
Keywords:Gene therapy, topical delivery, transdermal delivery, permeation enhancers, non-viral vectors, transfersomes, niosomes, nanoemulsions, biphasic vesicles, gemini-lipid nanoparticles. Abstract:Topical administration is attractive and non-invasive gene delivery approach. It is …Author: Mahmoud Elsabahy, Marianna Foldvari
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968787/
Gene-based therapeutics are broadly defined as using a vector to introduce nucleic acids into cells with the intention of altering gene expression to prevent, halt, or reverse a pathological process ().The skin is an attractive tissue for gene therapy for several reasons.Author: Emily Gorell, Ngon Nguyen, Alfred Lane, Zurab Siprashvili
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507026/
Jul 06, 2012 · INTRODUCTION. Basically gene therapy is an intracellular delivery of genomic materials (transgene) into specific cells to generate a therapeutic effect by correcting an existing abnormality or providing the cells with a new function.[] Different types of gene delivery systems may be applied in gene therapy to restore a specific gene function or turning off a special gene(s).
https://www.technologyreview.com/s/608898/five-ways-to-get-crispr-into-the-body/
Sep 22, 2017 · Five Ways to Get CRISPR into the Body Scientists are investigating a range of different delivery mechanisms for the gene-editing tool, from topical gels to skin grafts. by Emily Mullin
https://www.semanticscholar.org/paper/Lipid-mediated-gene-delivery-to-the-skin.-Geusens-Strobbe/5f3a50914044cf68792ea66927bcb08957da0dcd
Cutaneous gene delivery methods have been developed over the past decades as therapeutic strategies for the treatment of a variety of skin disorders. Both viral and non-viral techniques have been frequently described. Mainly due to safety concerns, the application of viral methods is being questioned and non-viral alternatives are gaining major interest. Lipid-based vesicles for the delivery ...
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