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https://www.slideshare.net/Aparajitha_Anne/gene-delivery-system
May 19, 2012 · GENE DELIVERY:• In most gene delivery studies a normal gene is inserted into the genome to replace an abnormal disease causing gene.• A carrier molecule called vector carries the therapeutic gene to patient’s target cells. Vectors generally used are viruses.•
https://www.ncbi.nlm.nih.gov/pubmed/19488722
Nanoparticle-mediated gene delivery. Jin S(1), Leach JC, Ye K. ... RNA, and siRNA into functionalized nanoparticles with little toxicity demonstrates a new era in pharmacotherapy for delivering genes selectively to tissues and cells. In this chapter, we highlight the basic concepts and applications of nonviral gene delivery using super ...Author: Sha Jin, John C. Leach, Kaiming Ye
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449975/
Apr 28, 2017 · 1. Introduction. Nanotechnology has seen many advances in recent years, both in terms of the development of novel materials, often with tunable properties [1,2] and applications in a growing number of areas.An area of particular interest, and the topic of this review, is gene therapy.Author: Michael K. Riley, Wilfred Vermerris
http://www.phys.sinica.edu.tw/TIGP-NANO/Course/2012_Spring/classnotes/NanoB_20120511.pdf
Non-viral Gene Delivery • Transfection- the delivery of foreign molecules such as DNA and RNA into eukaryotic cells • Naked DNA is not suitable for in-vivo transport of genetic materials-> degradation by serum nucleases • Ideal gene delivery system – Biocompatible – Non-immunogenic – Stable in blood stream – Protect DNA during ...
https://www.intechopen.com/books/advanced-technology-for-delivering-therapeutics/medicated-nanoparticle-for-gene-delivery
The basic mechanism involved in the gene delivery is an introduction of a gene encoding a functional protein altering the expression of an endogenous gene or owning the capacity to cure or prevent the progression of a disease. Nanoparticle surface features like particle shape and surface charge are having major roles in the gene delivery.Author: Sakthivel Lakshmana Prabu, Timmadonu Narasimman KuppusamiSuriyaprakash, Rathinasabapathy Thirumuruga...
https://www.slideshare.net/DeepaliPandey6/nanoparticles-75939063
May 13, 2017 · APPLICATIONS USED IN TARGETED DRUG DELIVERY TO BRAIN THERAPY USED IN TARGETING OF NANOPRATICLES TO EPITHELIAL CELLS IN THE GI TRACT USING LIGANDS USED IN BIO DECTECTION OF PATHOGENS STEM CELL THERAPY NANOPARTICLES FOR GENE DELIVERY CANCER THERAPY •Sriharitha, J Preethi, Hemanth S (2016).A Review on Nanoparticles …
https://www.researchgate.net/publication/305655393_Nanoparticles_in_Gene_Therapy
Nanoparticles in Gene Therapy. ... nanoparticles in ge ne delivery. Soon afte r they were described by Ale c Bangham in. 1965, l iposo mes have been under sc rutiny for use as a .
https://www.cell.com/molecular-therapy-family/methods/fulltext/S2329-0501(16)30165-6
Jan 01, 2016 · Gene therapy is a promising strategy for specific treatment of numerous gene-associated human diseases by intentionally altering the gene expression in pathological cells. A successful clinical application of gene-based therapy depends on an efficient gene delivery system. Many efforts have been attempted to improve the safety and efficiency of gene-based therapies. Nanoparticles have been ...Author: Jie Chen, Zhaopei Guo, Huayu Tian, Xuesi Chen
https://www.powershow.com/viewht/7aa0f-ZDc1Z/Nanotechnology_Based_Drug_Delivery_powerpoint_ppt_presentation
Drug delivery formulations involve low cost research compared that for discovery ... The spatial position of a solubilized drug in a micelle will depend on its ... – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 7aa0f-ZDc1Z
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