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https://www.nature.com/articles/nprot.2012.131
Nov 15, 2012 · Examples of anticipated results in which exosome-mediated siRNA delivery is evaluated by functional assays and imaging are also provided. The entire …Author: Samir El-Andaloussi, Samir El-Andaloussi, Yi Lee, Samira Lakhal-Littleton, Jinghuan Li, Yiqi Seow, C...
https://www.ncbi.nlm.nih.gov/pubmed/23154783
Exosome-mediated delivery of siRNA in vitro and in vivo. El-Andaloussi S(1), Lee Y, Lakhal-Littleton S, Li J, Seow Y, Gardiner C, Alvarez-Erviti L, Sargent IL, Wood MJ. Author information: (1)Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.Author: Samir El-Andaloussi, Samir El-Andaloussi, Yi Lee, Samira Lakhal-Littleton, Jinghuan Li, Yiqi Seow, C...
https://www.researchgate.net/publication/233423883_Exosome-mediated_delivery_of_siRNA_in_vitro_and_in_vivo
Exosome-mediated delivery of siRNA in vitro and in vivo Article in Nature Protocol 7(12):2112-26 · November 2012 with 881 Reads How we measure 'reads'
https://www.nature.com/articles/doi:10.1038/nprot.2012.131
Exosomes are promising tools for drug delivery across different biological barriers. Here we show how exosomes derived from cultured cells can be harnessed for delivery of siRNA in vitro and in vivo.Author: Samir El-Andaloussi, Samir El-Andaloussi, Yi Lee, Samira Lakhal-Littleton, Jinghuan Li, Yiqi Seow, C...
https://www.dpag.ox.ac.uk/publications/363843
Next, we detail crucial steps for loading siRNA into exosomes. Finally, we outline how to use exosomes to efficiently deliver siRNA in vitro and in vivo in mouse brain. Examples of anticipated results in which exosome-mediated siRNA delivery is evaluated by functional assays and imaging are also provided. The entire protocol takes ~3 weeks.Author: Samir El-Andaloussi, Samir El-Andaloussi, Yi Lee, Samira Lakhal-Littleton, Jinghuan Li, Yiqi Seow, C...
https://www.sciencedirect.com/science/article/pii/S0168365916306526
Functional exosome-mimic for delivery of siRNA to cancer: in vitro and in vivo evaluation Author links open overlay panel Zhaogang Yang a Jing Xie b Jing Zhu c Chen Kang c Chiling Chiang d Xinmei Wang a Xiaobing Wang e f Tairong Kuang a Feng Chen a Zhou Chen a Aili Zhang a Bo Yu a Robert J. Lee c Lesheng Teng b L. James Lee aAuthor: Zhaogang Yang, Jing Xie, Jing Zhu, Chen Kang, Chiling Chiang, Xinmei Wang, Xiaobing Wang, Xiaobing W...
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