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https://www.nature.com/articles/nature10358
Aug 31, 2011 · Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans. Caroline J. Breitbach 1,Author: Caroline J. Breitbach, James Burke, Derek Jonker, Derek Jonker, Joe Stephenson, Andrew R. Haas, Laur...
https://www.ncbi.nlm.nih.gov/pubmed/21886163
Aug 31, 2011 · The efficacy and safety of biological molecules in cancer therapy, such as peptides and small interfering RNAs (siRNAs), could be markedly increased if high concentrations could be achieved and amplified selectively in tumour tissues versus normal tissues after intravenous administration. This has not been achievable so far in humans.Author: Caroline J. Breitbach, James Burke, Derek Jonker, Derek Jonker, Joe Stephenson, Andrew R. Haas, Laur...
https://www.researchgate.net/profile/Jorge_Nieva/publication/51610875_Intravenous_delivery_of_a_multi-mechanistic_cancer-targeted_oncolytic_poxvirus_in_humans/links/53d90e1b0cf2e38c6331e268.pdf
Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans Caroline J. Breitbach 1 , James Burke 2 {, Derek Jonker 3,4 , Joe Stephenson 5 , Andrew R. Haas 6 , Laura Q ...Author: Caroline J. Breitbach, James Burke, Derek Jonker, Derek Jonker, Joe Stephenson, Andrew R. Haas, Laur...
http://adsabs.harvard.edu/abs/2011Natur.477...99B
The efficacy and safety of biological molecules in cancer therapy, such as peptides and small interfering RNAs (siRNAs), could be markedly increased if high concentrations could be achieved and amplified selectively in tumour tissues versus normal tissues after intravenous administration. This has not been achievable so far in humans.
https://www.researchgate.net/publication/51610875_Intravenous_delivery_of_a_multi-mechanistic_cancer-targeted_oncolytic_poxvirus_in_humans
Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans Article (PDF Available) in Nature 477(7362):99-102 · September 2011 with 609 Reads How we measure 'reads'
https://www.academia.edu/13768197/Intravenous_delivery_of_a_multi-mechanistic_cancer-targeted_oncolytic_poxvirus_in_humans
The efficacy and safety of biological molecules in cancer therapy, such as peptides and small interfering RNAs (siRNAs), could be markedly increased if high concentrations could be achieved and amplified selectively in tumour tissues versus normal
https://www.xconomy.com/wordpress/wp-content/images/2011/08/9-1-11-Nature-paper-JX594-intravenous.pdf
Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic ... delivery and replication were demonstrated in a patient with baseline antibodies to JX-594/ vaccinia (Supplementary Fig. 1
https://www.deepdyve.com/lp/nature-publishing-group-npg/intravenous-delivery-of-a-multi-mechanistic-cancer-targeted-oncolytic-XIzTVf48uu
Aug 31, 2011 · Read "Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans, Nature" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817877/
Aug 04, 2015 · This was the first clinical trial to use repeated doses of Pexa-Vec (pexastimogene devacirepvec; JX-594), or any other vaccinia or poxvirus, by intravenous infusion to treat patients with refractory, metastatic colorectal cancer. A biweekly schedule was chosen for the following reasons.Author: Se Hoon Park, Caroline J Breitbach, Jeeyun Lee, Joon Oh Park, Ho Yeong Lim, Won Ki Kang, Anne Moon, ...
https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(16)30280-5
Sep 01, 2015 · Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans.Author: Se Hoon Park, Caroline J Breitbach, Jeeyun Lee, Joon Oh Park, Ho Yeong Lim, Won Ki Kang, Anne Moon, ...
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