We have collected information about Exosome Gene Delivery for you. Follow the links to find out details on Exosome Gene Delivery.
https://systembio.com/applications/gene-delivery/
Choose any of our gene delivery-related services below—mix and match services to get what your research needs. Exosome Engineering—use exosomes as a non-viral method for gene delivery; Syn2Clone Custom Constructs—keep your hands off your pipettes with this service where you simply email us your gene sequence. We synthesize the gene and ...
https://www.exosome-rna.com/exosome-based-gene-therapy-for-microrna-delivery/
Dec 08, 2016 · Exosomes, unlike other vectors for gene delivery, present unique advantages such that exosomes are a cell-free natural system for ferrying RNA between cells, robust exosomal membrane can protect the RNA/gene of interest from digestion, and exosomes are rapidly taken up by target cells making them a more efficient vehicle for gene delivery.
https://www.sciencedirect.com/science/article/pii/S037851731730128X
Exosome delivery to recipient cells is a key step in mediating changes in cellular behavior (Lakhal and Wood, 2011, Vallhov et al., 2011). In addition, they also play essential roles in intercellular communication (Zhang and Chopp, 2016). For these natural characteristics, exosomes are being explored as drug and gene delivery vehicles.Author: Xin-Chi Jiang, Jian-Qing Gao
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826735/
Oct 05, 2015 · Exogenous DNA Loading into Extracellular Vesicles via Electroporation is Size-Dependent and Enables Limited Gene Delivery. ... are generally supportive of the findings of Kanada et al. 14 and suggest that MVs may hold enhanced potential for DNA delivery compared to smaller, exosome-like EVs.Author: Tek N. Lamichhane, Rahul S. Raiker, Steven M. Jay
https://www.ncbi.nlm.nih.gov/pubmed/28082074
Feb 01, 2017 · Adeno-associated virus (AAV) is a safe and effective vector for gene therapy for retinal disorders. Gene therapy for hearing disorders is not as advanced, in part because gene delivery to sensory hair cells of the inner ear is inefficient.Author: Bence György, Bence György, Cyrille Sage, Artur A. Indzhykulian, Deborah I. Scheffer, Alain R. Briss...
https://www.nature.com/articles/nprot.2012.131
Nov 15, 2012 · The use of small interfering RNAs (siRNAs) to induce gene silencing has opened a new avenue in drug discovery. However, their therapeutic potential is hampered by …Author: Samir El-Andaloussi, Samir El-Andaloussi, Yi Lee, Samira Lakhal-Littleton, Jinghuan Li, Yiqi Seow, C...
https://www.sciencedirect.com/science/article/pii/S0168365917308465
Herein, to develop an efficient cancer therapy, plasmid-encapsulating exosomes were created to introduce cas9 and sgRNA in cancer cells. We established the in vivo delivery vehicle for the disruption of PARP-1 expression by tumor-derived exosomes loaded with CRISPR/Cas9 against PARP-1 ().Inhibition of PARP-1 via the efficient delivery system of the genome editing tool enables a synergistic ...Author: Seung Min Kim, Yoosoo Yang, Yoosoo Yang, Seung Ja Oh, Yeonsun Hong, Yeonsun Hong, Minkoo Seo, Mihue ...
https://cen.acs.org/business/start-ups/Meet-exosome-rising-star-drug/96/i31
Meet the exosome, the rising star in drug delivery ... A group led by Casey Maguire at Massachusetts General Hospital has packaged an adeno-associated virus gene therapy inside an exosome—he ...
https://www.nature.com/articles/s42003-019-0300-2
Feb 08, 2019 · Exosomes are present in all fluids from living animals, including seawater and breathing mammals, suggesting that exosome-mediated horizontal gene transfer is …Author: Ryuichi Ono, Yukuto Yasuhiko, Ken-ichi Aisaki, Satoshi Kitajima, Jun Kanno, Yoko Hirabayashi
https://www.onlinelibrary.wiley.com/doi/full/10.1002/advs.201700611
Jan 30, 2018 · Consistently, Runx2 expression was significantly decreased upon hybrid exosome mediated CRISPR/dCas9 targeted Runx2 delivery (Figure 5D), which indicated that CRISPR system could be loaded into the hybrid exosomes and delivered to recipient cells for gene engineering.Author: Yao Lin, Jiahua Wu, Weihuai Gu, Yulei Huang, Zhongchun Tong, Lijia Huang, Jiali Tan
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